Three-dimensional computed tomography analysis of variations in the middle hepatic vein tributaries: proposed new classification

Surgery Today
Hiroto KayashimaYoshihiko Maehara

Abstract

To evaluate the anatomical variations in the middle hepatic vein tributaries (V5/V8) for determining the reconstruction strategy in right lobe living donor liver transplantation (LDLT). The V5/V8 variations were examined in 268 patients and were classified into three and two types, respectively. The reconstruction rate (RR), patency rate (PR) and clinical outcomes were retrospectively evaluated in 46 right lobe LDLT cases. In terms of V5 variations, the RR and PR were significantly higher for type 2 than type 3 (82.6 vs. 44.4 % and 73.7 vs. 25.0 %, respectively). The alanine aminotransferase level on postoperative day (POD) 5 in the V5 patent group was significantly lower than in the occluded group (123 vs. 191 IU/dL). Regarding V8 variations, the RR and PR were significantly higher for type 1 than type 2 (44.4 vs. 17.6 % and 75.0 vs. 33.3 %, respectively). The aspartate aminotransferase level on POD 3 was significantly lower in the V8 patent group than in the occluded group (50 vs. 121 IU/dL). For right lobe grafts with single large V5 (type 2) or V8 (type 1) variations, reconstruction is necessary. Our new classification of the MHV tributaries is useful for determining the reconstruction strategy to use in right lobe LDLT.

References

Aug 26, 1989·Lancet·S RaiaS Mies
Mar 6, 1998·Annals of Surgery·S KawasakiS Miyagawa
Aug 26, 1998·Annals of Surgery·H P GrewalJ M Millis
Nov 8, 2001·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·M Ben-HaimC M Miller
Feb 18, 2003·Transplantation·Sheung-Tat FanMasatoshi Makuuchi
Feb 28, 2003·The New England Journal of Medicine·Robert S BrownJay H Hoofnagle
Sep 6, 2003·Lancet·Koji UmeshitaJapanese Liver Transplantation Society
Sep 23, 2003·Transplantation·Nobuhisa AkamatsuMasatoshi Makuuchi
Jun 24, 2004·Annals of Surgery·Chung-Mau LoJohn Wong
Nov 30, 2005·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Yusuke YonemuraYoshihiko Maehara
Aug 30, 2008·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Hiroto KayashimaYoshihiko Maehara
Feb 10, 2009·Transplantation·Akinobu TaketomiYoshihiko Maehara
Apr 24, 2009·Transplant International : Official Journal of the European Society for Organ Transplantation·Takasuke FukuharaYoshihiko Maehara

Citations

Jun 11, 2015·World Journal of Surgery·Yuki BekkiYoshihiko Maehara
Apr 27, 2020·The British Journal of Surgery·A WatanabeKen Shirabe
Jun 20, 2018·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Jean-Baptiste CazauranGuillaume Passot

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