PMID: 11337294May 19, 2001Paper

Three-dimensional grayscale ultrasound: evaluation of prostate cancer compared with benign prostatic hyperplasia

Urology
J P SedelaarJ J de la Rosette

Abstract

To compare the accuracy of the detection, localization, and staging of prostate cancer using transrectal three-dimensional (3D) grayscale ultrasonography (3D-US) with conventional transrectal two-dimensional grayscale ultrasonography (2D-US). Fifty patients with clinical localized prostate cancer scheduled to undergo radical retropubic prostatectomy and 50 patients with clinical benign prostatic hyperplasia underwent transrectal ultrasound investigations (2D and 3D). The prostate images were retrospectively analyzed by two ultrasound experts unaware of the clinical findings. The images of the prostate cancer group were correlated with the whole-mount histologic specimens of the prostate. All percentages are given for experts 1 and 2. The sensitivity, specificity, and accuracy for the detection of prostate cancer without considering the definitive localization of the tumor for 2D-US was 72% and 76%, 50% and 54%, and 63% and 64%, respectively; for 3D-US, the rates were 82% and 88%, 40% and 42%, and 61% and 65%. The sensitivity, specificity, and accuracy of the combination of 2D-US with 3D-US was 88% and 90%, 36% and 38%, and 62% and 64%, respectively. The sensitivity, specificity, and accuracy for the exact localization of the pr...Continue Reading

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Citations

Aug 1, 2007·Der Urologe. Ausg. A·M SeitzC Stief
Nov 19, 2004·World Journal of Urology·S S MehtaF C Hamdy
Feb 14, 2006·Nature Clinical Practice. Urology·Anwar R PadhaniDavid O Cosgrove
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Jul 11, 2006·The Urologic Clinics of North America·Gilad E Amiel, Kevin M Slawin
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Sep 11, 2012·BJU International·Giovanna RussoHessel Wijkstra
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May 2, 2009·The Urologic Clinics of North America·Stavros GravasJean de la Rosette
Feb 7, 2007·Ultrasound in Medicine & Biology·Philippe BonninEvelyne Dupuy
Aug 20, 2010·Urology·Edouard J TrabulsiEthan J Halpern
Jul 13, 2002·Expert Review of Anticancer Therapy·Beverley A Wilkinson, Freddie C Hamdy
Oct 24, 2009·Journal of Medical Engineering & Technology·S CandefjordO A Lindahl
Jan 15, 2003·Der Urologe. Ausg. A·M ZachariasP Fornara
Feb 6, 2016·World Journal of Urology·Maudy GayetHessel Wijkstra

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