Three-dimensional kinematics at the level of the oculomotor plant

The Journal of Neuroscience : the Official Journal of the Society for Neuroscience
Eliana M KlierDora E Angelaki

Abstract

Motor systems often require that superfluous degrees of freedom be constrained. For the oculomotor system, a redundancy in the degrees of freedom occurs during visually guided eye movements and is solved by implementing Listing's law and the half-angle rule, kinematic constraints that limit the range of eye positions and angular velocities used by the eyes. These constraints have been attributed either to neurally generated commands or to the physical mechanics of the eye and its surrounding muscles and tissues (i.e., the ocular plant). To directly test whether the ocular plant implements the half-angle rule, critical to the maintenance of Listing's law, we microstimulated the abducens nerve with the eye at different initial vertical eye positions. We report that the electrically evoked eye velocity exhibits the same eye position dependence as seen in visually guided smooth-pursuit eye movements. These results support an important role for the ocular plant in providing a solution to the degrees-of-freedom problem during eye movements.

Citations

Nov 26, 2009·Experimental Brain Research·Andrea M Green, Dora E Angelaki
Sep 29, 2011·Experimental Brain Research·Min WeiShawn D Newlands
Nov 26, 2010·Journal of Neurophysiology·Eliana M KlierDora E Angelaki
Mar 20, 2009·Journal of Neurophysiology·Sean R AndersonPaul Dean
May 9, 2008·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Fatema F GhasiaDora E Angelaki
Sep 21, 2012·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Eliana M KlierDora E Angelaki
Sep 1, 2014·Journal of AAPOS : the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus·Joseph L Demer
Apr 5, 2011·Annual Review of Neuroscience·J Douglas CrawfordW Pieter Medendorp
May 19, 2007·The Journal of Physiology·Carlos R Cassanello, Vincent P Ferrera
Jan 28, 2010·American Journal of Ophthalmology·Joseph L Demer
Mar 4, 2008·Journal of AAPOS : the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus·Joseph L Demer
Sep 29, 2011·Annals of the New York Academy of Sciences·Matthew J ThurtellMark F Walker
Sep 29, 2011·Annals of the New York Academy of Sciences·Joseph L DemerLawrence Yoo
Jul 19, 2013·Journal of Ophthalmology·Fatema F Ghasia, Aasef G Shaikh
Jun 27, 2015·Frontiers in Computational Neuroscience·Mehdi Daemi, J Douglas Crawford
Feb 27, 2007·Vision Research·Jing TianMark F Walker
Aug 23, 2008·Progress in Brain Research·Joseph L DemerShaheen Karim
Nov 3, 2006·Journal of Neurophysiology·Eliana M KlierJ Douglas Crawford
May 25, 2007·Journal of Neurophysiology·Mark F WalkerDavid S Zee
Jul 1, 2011·Journal of Neurophysiology·Bernhard J M Hess, Jakob S Thomassen
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Dec 5, 2019·Investigative Ophthalmology & Visual Science·Joel M Miller
Oct 7, 2006·Journal of Pediatric Ophthalmology and Strabismus·Joseph L Demer
May 25, 2021·PLoS Computational Biology·Akhil JohnAlexandre Bernardino

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