Abstract
Elucidation of the electrophysiological mechanisms of nonsustained ventricular tachycardia (VT) in humans is required to define the relationship between nonsustained VT and sustained VT. This goal requires, at least in part, analysis of transmural ventricular activation in patients with both sustained and nonsustained VTs. We analyzed three-dimensional intraoperative cardiac maps of extrastimuli and beats during 44 nonsustained VTs and the initiating beats of 6 sustained VTs from six patients with healed myocardial infarcts who were undergoing arrhythmia surgery. The coupling interval, total activation time, and diastolic interval of each extrastimulus and beat of nonsustained VT were compared with counterparts during sustained VT. Sites activated last during extrastimuli initiating nonsustained or sustained VTs occurred in the same region, and activation times were comparable. However, the site of earliest activation during the initial or subsequent beats of nonsustained VT was discordant from the site activated earliest during the first and subsequent beats of sustained VT in 74% of cases. The mean variance in coupling interval, but not total activation time or diastolic interval, was significantly greater for VT that termina...Continue Reading
References
Jul 1, 1987·Journal of the American College of Cardiology·T J WallerL N Horowitz
Jun 16, 1983·The New England Journal of Medicine·C D SwerdlowJ W Mason
Jun 1, 1995·Journal of the American College of Cardiology·E DownarL Harris
Nov 1, 1993·Progress in Cardiovascular Diseases·A E BuxtonD Packer
Aug 1, 1993·Journal of Cardiovascular Electrophysiology·R L Mitra, A E Buxton
Sep 1, 1993·Circulation·H J DuffD G Wyse
Jun 3, 1997·Circulation·S M PogwizdM E Cain
Citations
Oct 18, 2000·Pharmacology & Therapeutics·R A Altschuld, G E Billman
Dec 12, 2001·Journal of the American College of Cardiology·J E BurnesY Rudy
Oct 17, 2002·Journal of Cardiovascular Electrophysiology·Ping JiaYoram Rudy
Apr 5, 2000·Journal of Cardiovascular Electrophysiology·G E MorleyJ Jalife
Aug 2, 2000·Journal of Cardiovascular Electrophysiology·S ZhangR E Ideker
Apr 12, 2005·Annual Review of Pharmacology and Toxicology·R Dale BrownCarlin S Long
Jan 20, 2011·Internal Medicine·Yoshiaki KanekoMasahiko Kurabayashi
Feb 23, 2013·Basic Research in Cardiology·Yukiomi TsujiDobromir Dobrev
Mar 31, 2009·Mathematical Biosciences·S ScacchiB Taccardi
Oct 4, 2007·Progress in Biophysics and Molecular Biology·K H W J Ten Tusscher, A V Panfilov
Sep 1, 2006·IEEE Transactions on Bio-medical Engineering·Chenguang LiuBin He
Jun 14, 2012·IEEE Transactions on Medical Imaging·Chenguang LiuBin He
Dec 30, 2010·IEEE Transactions on Bio-medical Engineering·Chenguang LiuBin He
Jan 27, 2007·Cardiovascular Research·Mark E Anderson
Feb 10, 2009·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Mina AttinSteven M Pogwizd
May 26, 2017·PloS One·Xu-Wen ZhaiQing-Hua Liu
Dec 13, 2005·Journal of Internal Medicine·M E Anderson
Aug 17, 2019·American Journal of Physiology. Heart and Circulatory Physiology·Mark L TrewBruce H Smaill
Oct 9, 1999·Journal of Cardiovascular Electrophysiology·G E MorleyJ Jalife
Nov 18, 2004·Angiology·Bonpei TakaseAkira Kurita
Dec 3, 2021·International Heart Journal·Qinghua LiuJimin Cao