Three-dimensional optical topography of brain activity in infants watching videos of human movement.

Physics in Medicine and Biology
Teresa CorreiaAdam P Gibson

Abstract

We present 3D optical topography images reconstructed from data obtained previously while infants observed videos of adults making natural movements of their eyes and hands. The optical topography probe was placed over the temporal cortex, which in adults is responsible for cognitive processing of similar stimuli. Increases in oxyhaemoglobin were measured and reconstructed using a multispectral imaging algorithm with spatially variant regularization to optimize depth discrimination. The 3D optical topography images suggest that similar brain regions are activated in infants and adults. Images were presented showing the distribution of activation in a plane parallel to the surface, as well as changes in activation with depth. The time-course of activation was followed in the pixel which demonstrated the largest change, showing that changes could be measured with high temporal resolution. These results suggest that infants a few months old have regions which are specialized for reacting to human activity, and that these subtle changes can be effectively analysed using 3D optical topography.

References

Dec 18, 2001·NMR in Biomedicine·E YacoubX Hu
Oct 12, 2002·Physics in Medicine and Biology·Tsuyoshi YamamotoHideaki Koizumi
Sep 10, 2003·Proceedings of the National Academy of Sciences of the United States of America·Gentaro TagaHideaki Koizumi
Jul 10, 2007·Proceedings of the National Academy of Sciences of the United States of America·Benjamin W ZeffJoseph P Culver
Aug 1, 2007·Physiological Measurement·Andy AdlerWilliam R B Lionheart
Nov 13, 2007·Journal of Biomedical Optics·Elizabeth M C Hillman
Apr 3, 2008·Human Brain Mapping·Frank Van Overwalle
Sep 10, 2001·Optics Express·A BluestoneA Hielscher
Jul 2, 2009·Journal of Biomedical Optics·Teresa CorreiaJeremy Hebden
Jul 8, 2009·Philosophical Transactions. Series A, Mathematical, Physical, and Engineering Sciences·Adam Gibson, Hamid Dehghani
Jul 28, 2009·Child Development·Sarah Lloyd-FoxMark H Johnson
Jul 28, 2009·NeuroImage·Brian R White, Joseph P Culver
Jul 28, 2009·Neuroscience and Biobehavioral Reviews·S Lloyd-FoxC E Elwell
Aug 1, 2009·NeuroImage·Anna CustoWilliams Wells
Feb 10, 2010·Proceedings of the National Academy of Sciences of the United States of America·Kâmil Uludag
Oct 20, 2010·Journal of Cognitive Neuroscience·Sarah Lloyd-FoxMark H Johnson
Jul 1, 2010·Reports on Progress in Physics·T DurduranA G Yodh

❮ Previous
Next ❯

Citations

Oct 24, 2017·The European Journal of Neuroscience·S Lloyd-FoxUNKNOWN BASIS Team
Jul 16, 2016·Journal of Biomedical Optics·Yoko Hoshi, Yukio Yamada

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Advances in Experimental Medicine and Biology
Maria D PapademetriouClare E Elwell
Conference Proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society
Kalle KotilahtiIlkka Nissila
Conference Proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society
A D Klose, B J Beattie
© 2022 Meta ULC. All rights reserved