PMID: 15379027Sep 24, 2004Paper

Three-dimensional seed reconstruction from an incomplete data set for prostate brachytherapy

Physics in Medicine and Biology
Sreeram NarayananRobert J Marks

Abstract

Intra-operative dosimetry in prostate brachytherapy requires 3D coordinates of the implanted, radioactive seeds. Since CT is not readily available during the implant operation, projection x-rays are commonly used for intra-operative seed localization. Three x-ray projections are usually used. The requirement of the current seed reconstruction algorithms is that the seeds must be identified on all three projections. However, in practice this is often difficult to accomplish due to the problem of heavily clustered and overlapping seeds. We have developed an algorithm that permits seed reconstruction from an incomplete data set. Instead of all three projections, the new algorithm requires only one of the three projections to be complete. Furthermore, even if all three projections are incomplete, it can reconstruct 100% of the implanted seeds depending on how the undetected seeds are distributed among the projections. The method utilizes the principles of epipolar imaging geometry and pseudo-matching of the undetected seeds. The algorithm was successfully applied to a large number of clinical cases where seeds imperceptibly overlap in some projections.

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Mar 10, 2004·Physics in Medicine and Biology·Steve T LamSreeram Narayanan

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Citations

Jul 21, 2011·Physics in Medicine and Biology·Junghoon LeeJerry L Prince
Dec 24, 2005·Medical Physics·Ameet Kumar JainGabor Fichtinger
Oct 14, 2011·Medical Physics·Ehsan DehghanGabor Fichtinger
Apr 19, 2007·Medical Physics·Frank-André SiebertGyörgy Kovács
Aug 27, 2005·Medical Physics·Marcel SteggerdaHenk van der Poel
Apr 15, 2008·Medical Physics·Gregory WhiteheadJim Ji
Jul 13, 2012·Medical Image Analysis·Ehsan DehghanGabor Fichtinger
Sep 6, 2008·Medical Engineering & Physics·Ju-Young HongSiyong Kim
Dec 16, 2006·IEEE Transactions on Medical Imaging·Ismail B TutarYongmin Kim
Sep 28, 2007·IEEE Transactions on Medical Imaging·Vikas SinghMatthew Podgorsak
Jul 17, 2009·IEEE Transactions on Medical Imaging·Junghoon LeeGabor Fichtinger
Jul 21, 2010·IEEE Transactions on Medical Imaging·Junghoon LeeJerry L Prince
Aug 21, 2007·International Journal of Radiation Oncology, Biology, Physics·Peter F OrioKent E Wallner
Apr 22, 2005·Physics in Medicine and Biology·Steve T LamSreeram Narayanan
May 20, 2005·Physics in Medicine and Biology·Martin J Murphy, Dorin A Todor
Jul 1, 2005·Medical Physics·Marcel SteggerdaHenk van der Poel

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