Three-Dimensional self-assembly of branching nanofibers over micro fibrous trunk by Coaxial Electrospinning

Preprints.org
Zahra Bazrafshan, George K Stylios

Abstract

One step fabrication of 3D fiber stack of Acid Soluble Collagen-g-P(MMA-co-EA)/Nylon 6 formed by coaxial electrospinning is obtained through controlling the experimental conditions. The resulting 3D collagen based nanofibrous stack shows two distinguished assemblies: randomly oriented microfibers of 6.9±2.2µm diameter and dense branched nanofibers of 216±49 nm diameter. The fiber stacks can be accumulated within 20 min via single needle coaxial electrospinning. The stacks can obtain an average height of 4 cm. The self-assembly mechanism of the fiber stack and the effect of experimental conditions were also investigated. The self-assembled 3D fiber underpinned by the promising potential due to its large surface area and pore size for many practical end uses such as tissue engineering, Textiles, filtration require the properties of nanotexture of collagen based macrostructure.

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