Three-dimensional subzone-based reconstruction algorithm for MR elastography

Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine
Elijah E W Van HoutenK D Paulsen

Abstract

Accurate characterization of harmonic tissue motion for realistic tissue geometries and property distributions requires knowledge of the full three-dimensional displacement field because of the asymmetric nature of both the boundaries of the tissue domain and the location of internal mechanical heterogeneities. The implications of this for magnetic resonance elastography (MRE) are twofold. First, for MRE methods which require the measurement of a harmonic displacement field within the tissue region of interest, the presence of 3D motion effects reduces or eliminates the possibility that simpler, lower-dimensional motion field images will capture the true dynamics of the entire stimulated tissue. Second, MRE techniques that exploit model-based elastic property reconstruction methods will not be able to accurately match the observed displacements unless they are capable of accounting for 3D motion effects. These two factors are of key importance for MRE techniques based on linear elasticity models to reconstruct mechanical tissue property distributions in biological samples. This article demonstrates that 3D motion effects are present even in regular, symmetric phantom geometries and presents the development of a 3D reconstructio...Continue Reading

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Citations

Dec 25, 2002·Journal of Magnetic Resonance Imaging : JMRI·Elijah E W Van HoutenKeith D Paulsen
Oct 13, 2001·NMR in Biomedicine
Jun 10, 2011·Physics in Medicine and Biology·M D J McGarryK D Paulsen
Oct 20, 2012·Physics in Medicine and Biology·John B WeaverKeith D Paulsen
Jan 10, 2012·Physics in Medicine and Biology·M M Doyley
Jun 30, 2005·Medical Physics·Michael I MigaJao J Ou
Jun 2, 2011·Medical Physics·Elijah E W Van HoutenK D Paulsen
Jul 29, 2006·Medical Physics·Christine TannerD Rodney Hose
Oct 9, 2012·Medical Physics·M D J McGarryK D Paulsen
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Sep 25, 2012·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Temel K YasarRichard L Magin
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