Three-dimensional surface reconstruction and panoramic optical mapping of large hearts

IEEE Transactions on Bio-medical Engineering
Matthew W KayJack Rogers

Abstract

Optical mapping of electrical activity from the surface of the heart is a powerful tool for studying complex arrhythmias. However, a limitation of traditional optical mapping is that the mapped region is restricted to the field of view of the sensor, which makes it difficult to track electrical waves as they drift in and out of view. To address this, we developed an optical system that panoramically maps epicardial electrical activity in three dimensions. The system was engineered to accomodate hearts comparable in size to human hearts. It is comprised of a surface scanner that measures epicardial geometry and a panoramic fluorescence imaging system that records electrical activity. Custom software texture maps the electrical data onto a reconstructed epicardial surface. The result is a high resolution, spatially contiguous, mapping dataset. In addition, the three-dimensional positions of the recording sites are known, making it possible to accurately measure parameters that require geometric information, such as propagation velocity. In this paper, we describe the system and demonstrate it by mapping a swine heart.

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Citations

Aug 14, 2012·Pflügers Archiv : European journal of physiology·Peter LeeChristian Bollensdorff
Jul 26, 2008·Annals of Biomedical Engineering·Qing LouIgor R Efimov
Oct 1, 2006·Journal of Biological Physics·Arun V HoldenWing Chiu Tong
Jul 17, 2012·American Journal of Physiology. Heart and Circulatory Physiology·Jacob I LaughnerIgor R Efimov
Apr 25, 2006·American Journal of Physiology. Heart and Circulatory Physiology·Matthew W KayJack M Rogers
Jul 24, 2012·American Journal of Physiology. Heart and Circulatory Physiology·Jacob I LaughnerIgor R Efimov
Sep 29, 2011·Journal of Visualized Experiments : JoVE·Qing LouIgor R Efimov
Sep 18, 2007·Journal of Biomedical Optics·Fujian QuIgor R Efimov
Oct 26, 2013·IEEE Reviews in Biomedical Engineering·Bas J Boukens, Igor R Efimov
Mar 13, 2008·IEEE Transactions on Bio-medical Engineering·Dale W EvertsonJohn P Wikswo
Jan 16, 2004·IEEE Transactions on Bio-medical Engineering·Jack M Rogers
Jan 18, 2005·IEEE Transactions on Bio-medical Engineering·Matthew W Kay, Richard A Gray
Dec 28, 2010·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Jean ProvostElisa E Konofagou
Jan 31, 2006·Biophysical Journal·Martin J BishopDavid J Gavaghan
May 24, 2016·Progress in Biophysics and Molecular Biology·C KangI R Efimov
Jul 28, 2016·Biophysical Journal·Hanyu ZhangJack M Rogers
Nov 13, 2007·Journal of Electrocardiology·Martin J BishopBlanca Rodriguez
Jan 20, 2018·American Journal of Physiology. Heart and Circulatory Physiology·Matthieu Ruiz, Philippe Comtois
Feb 15, 2018·Scientific Reports·Christopher GloschatIgor R Efimov
Jan 29, 2021·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Kenichi IijimaJack M Rogers

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