PMID: 9161692Mar 1, 1997Paper

Three-dimensional ultrastructure of the perivascular space in the rat thymus

Archives of Histology and Cytology
T Ushiki, M Takeda

Abstract

The overall architecture and structure of the perivascular space in the rat thymus were studied by light microscopy using silver-impregnated sections and sections stained immunohistochemically with anti-cytokeratin antibody, and by transmission and scanning electron microscopy (TEM and SEM). In silver-impregnated sections, the perivascular space was delimited by a thin sheath of delicate argyrophilic fibers from the thymic parenchyma in the cortico-medullary region and medulla. This space was continuous with the septal connective tissue, indicating that this was the connective tissue compartment rather than with the epithelial compartment of the parenchyma. In the medulla, the perivascular space widened at places, where the argyrophilic sheath was often discontinuous and the boundary between the perivascular space and parenchyma was indistinct. Lymphatics were located in the perivascular space of the corticomedullary region and sometimes in the wide perivascular space of the medulla. The presence of a thymic epithelial sheath surrounding the perivascular space was confirmed by light microscopy of anti-cytokeratin antibody immunostained sections and by TEM. SEM observations revealed three-dimensionally that the epithelial sheath...Continue Reading

Citations

May 18, 2011·The Journal of Experimental Medicine·Béatrice BréartSusan R Schwab
Jan 23, 2004·The Journal of Alternative and Complementary Medicine : Research on Paradigm, Practice, and Policy·Wentao MaLianxin Cao
Aug 24, 2007·Experimental Diabetes Research·Stephen G Schwartz, Harry W Flynn
May 1, 2008·PloS One·Magali IrlaCatherine Nguyen
Nov 5, 2013·Clinical & Developmental Immunology·Xi XuQing Ge
Nov 21, 2000·Seminars in Immunology·A M Norment, M J Bevan
Apr 24, 2014·Computational and Structural Biotechnology Journal·Xi Xu, Qing Ge
Feb 15, 2019·Cell and Tissue Research·Reinhard Pabst
Dec 12, 2003·Nature Reviews. Immunology·Howard T Petrie
Apr 13, 2019·Immunological Reviews·Dhaval DixitSusan R Schwab
Jan 22, 2004·The Journal of Immunology : Official Journal of the American Association of Immunologists·Mylène Vivinus-NebotAlain Bernard
Feb 2, 2021·Frontiers in Immunology·Takeshi Nitta, Hiroshi Takayanagi

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