Three distinct cases of copper deficiency in hospitalized pediatric patients

Clinical Pediatrics
Karolina DembinskiLisa Rodriguez

Abstract

Although copper deficiency is a rare occurrence in the developed world, attention should be given to the proper supplementation of minerals to at-risk pediatric patients. This study presents 3 distinct cases of copper deficiency in hospitalized patients aged 14 months, 6 years, and 12 years. Two patients had short bowel syndrome, requiring prolonged parenteral nutrition or complex intravenous fluid supplementation. The third patient was severely malnourished. Copper deficiency manifested in all of our patients as either microcytic anemia or pancytopenia with myelodysplastic syndrome. Copper deficiency is an important diagnosis to be considered in patients with prematurity, parenteral nutrition dependency, malabsorption, and/or those with malnutrition. More studies are needed to establish appropriate amounts of copper supplementation to replenish copper stores in deficient patients.

References

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Citations

Feb 13, 2014·Annals of the New York Academy of Sciences·Joseph R Prohaska
Apr 1, 2017·Nutrition in Clinical Practice : Official Publication of the American Society for Parenteral and Enteral Nutrition·Callum Livingstone
Dec 19, 2014·Nutrition in Clinical Practice : Official Publication of the American Society for Parenteral and Enteral Nutrition·Jay M Mirtallo
May 18, 2019·Archives of Disease in Childhood·Harriet Barraclough, Katarzyna Cooke
Apr 1, 2017·Nutrition in Clinical Practice : Official Publication of the American Society for Parenteral and Enteral Nutrition·Callum Livingstone
Jul 1, 2018·Annals of Hematology·Zin W MyintHayder Saeed
Oct 23, 2019·JPEN. Journal of Parenteral and Enteral Nutrition·Heitor Pons LeiteMaria Fernanda Carvalho de Camargo

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