Three IMRT advanced planning tools: A multi-institutional side-by-side comparison

Journal of Applied Clinical Medical Physics
Lan LuPing Xia

Abstract

To assess three advanced radiation therapy treatment planning tools on the intensity-modulated radiation therapy (IMRT) quality and consistency when compared to the clinically approved plans, referred as manual plans, which were planned without using any of these advanced planning tools. Three advanced radiation therapy treatment planning tools, including auto-planning, knowledge-based planning, and multiple criteria optimization, were assessed on 20 previously treated clinical cases. Three institutions participated in this study, each with expertise in one of these tools. The twenty cases were retrospectively selected from Cleveland Clinic, including five head-and-neck (HN) cases, five brain cases, five prostate with pelvic lymph nodes cases, and five spine cases. A set of general planning objectives and organs-at-risk (OAR) dose constraints for each disease site from Cleveland Clinic was shared with other two institutions. A total of 60 IMRT research plans (20 from each institution) were designed with the same beam configuration as in the respective manual plans. For each disease site, detailed isodoseline distributions and dose volume histograms for a randomly selected representative case were compared among the three resear...Continue Reading

References

Jan 30, 2002·Physics in Medicine and Biology·Carl Graham Rowbottom, Steve Webb
Mar 1, 2003·Physics in Medicine and Biology·Qiuwen WuRadhe Mohan
Oct 1, 2003·Physics in Medicine and Biology·Robert JerajThomas R Mackie
Jun 9, 2004·International Journal of Radiation Oncology, Biology, Physics·Ping XiaLynn J Verhey
Nov 17, 2004·Medical Physics·Eduard Schreibmann, Lei Xing
Aug 15, 2006·International Journal of Radiation Oncology, Biology, Physics·Margie A HuntNancy Lee
Oct 7, 2006·Medical Physics·David L CraftThomas R Bortfeld
Mar 31, 2007·International Journal of Radiation Oncology, Biology, Physics·David CraftThomas Bortfeld
Sep 26, 2007·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Christian ThiekeThomas Bortfeld
Oct 9, 2007·International Journal of Radiation Oncology, Biology, Physics·David CraftThomas Bortfeld
Oct 29, 2008·International Journal of Radiation Oncology, Biology, Physics·Theodore S HongThomas R Bortfeld
Jun 30, 2009·Journal of the American College of Radiology : JACR·Indra J DasPeter A Johnstone
Feb 26, 2010·Clinical Oncology : a Journal of the Royal College of Radiologists·V J EstallN G Burnet
Aug 31, 2010·International Journal of Radiation Oncology, Biology, Physics·Binbin WuTodd McNutt
Jan 18, 2011·International Journal of Radiation Oncology, Biology, Physics·Thomas G PurdieMichael B Sharpe
Feb 1, 2011·International Journal of Radiation Oncology, Biology, Physics·Kevin L MooreSasa Mutic
Feb 9, 2011·International Journal of Radiation Oncology, Biology, Physics·David L CraftThomas R Bortfeld
Feb 20, 2016·Journal of Applied Clinical Medical Physics·Irene HazellCarsten Brink
Mar 5, 2016·Medical Physics·Justin J BoutilierTimothy C Y Chan
May 12, 2016·Journal of Applied Clinical Medical Physics·Dawn GintzVladimir Feygelman
Sep 19, 2016·Clinical and Translational Radiation Oncology·Christian Rønn HansenCarsten Brink

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