Three pairs of diastereoisomeric flavanone glycosides from Viscum articulatum

Fitoterapia
Haizhen LiDongmei Ren

Abstract

Phytochemical examination of the leaves and stems of Viscum articulatum resulted in the isolation of three pairs of new flavanone glycosides, 2R/2S-viscarticulide A-C (1a/1b-3a/3b), together with eight known compounds (7-14). Their structures were established by extensive spectroscopic data analyses. The diastereoisomers were separated by HPLC on a chiral phase and the absolute configuration at C-2 was determined by circular dichroism (CD) spectra. The protective effects of compounds 1-3 against H2O2-induced cytotoxicity with EA.hy926 cells were tested. The results showed that compounds 1-3 improved the survival of EA.hy926 cells after H2O2 exposure at the tested concentrations.

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Citations

Mar 2, 2016·Phytomedicine : International Journal of Phytotherapy and Phytopharmacology·Lijuan ZhaoDongmei Ren
Apr 12, 2016·International Journal of Biological Macromolecules·Raed AbdennabiLassaad Belbahri
Feb 9, 2018·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Qing LiZhichao Lu
Oct 17, 2017·The Journal of Pharmacy and Pharmacology·Bhishma P Patel, Pawan K Singh
Jan 31, 2020·Natural Product Research·Miaomiao WangDongmei Ren
Feb 5, 2021·Fitoterapia·Huaran ZhangDongmei Ren
Aug 15, 2021·Biomedical Chromatography : BMC·Xu-Ya WeiLu-Qi Huang

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