Three sibs with microcephaly, clubfeet and agenesis of corpus callosum: a new genetic syndrome?

American Journal of Medical Genetics. Part a
Vered ShkalimRachel Straussberg


Clubfoot is a common birth deformity, and agenesis of the corpus callosum is one of the most prevalent brain malformations. We describe three sibs of Arab origin, who were born with clubfeet, agenesis of corpus callosum, and minor anomalies. Two of them were born with microcephaly. This phenotype may represent a novel autosomal recessive genetic condition.


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May 26, 2009·Nature Genetics·Xavier H JaglinJamel Chelly

Related Concepts

Multiple Congenital Anomalies
Congenital Clubfoot
Magnetization Transfer Contrast Imaging
Genealogical Tree
Corpus Callosum Malformation
Corpus Callosum
Genetic Syndrome

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