Three women with lupus transverse myelitis: case reports and differential diagnosis

Archives of Physical Medicine and Rehabilitation
D V InslichtK T Ragnarsson

Abstract

Although the association between transverse myelitis (TM) and systemic lupus erythematosus (SLE) has been reported previously, it remains a rare clinical condition. Our experience treating three women with lupus TM within a few months is presented. In each patient, spinal cord dysfunction was accompanied by laboratory or clinical evidence of SLE. Further neurologic manifestations, such as optic neuritis, developed in all patients, suggesting other diagnoses, including multiple sclerosis (MS), Devic's syndrome, and lupoid sclerosis. The outcomes for these three women were severe disability, death, and moderate disability, respectively. The severity of outcome did not seem to correlate with the timing or intensity of treatment. Physiatrists should be aware of the potential for neurologic progression in lupus TM, because patients with this condition invariably require rehabilitation.

References

Jul 1, 1988·Neurology·M F Mendez, S Pogacar
Apr 1, 1968·Archives of Neurology·A S Penn, A J Rowan
Aug 1, 1982·Archives of Neurology·P Dore-DuffyR B Zurier
Aug 1, 1995·Clinical Neurology and Neurosurgery·C C Mok, C S Lau
Apr 1, 1995·Archives of Physical Medicine and Rehabilitation·K F ChanM L Boey
Jun 1, 1993·American Journal of Physical Medicine & Rehabilitation·M D Klaiman, S D Miller

❮ Previous
Next ❯

Citations

Jun 16, 2007·Rheumatology International·Sigliti-Henrietta PelidouAthanassios P Kyritsis
Mar 29, 2008·Postgraduate Medical Journal·A Theodoridou, L Settas
Oct 15, 2009·Rheumatology International·Briele KeisermanHenrique Luiz Staub
Aug 28, 2009·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Savita Rani Singhal, Smiti Nanda
Jun 6, 2015·BMJ Case Reports·Joana Azevedo DuarteJosé Delgado Alves
Apr 9, 2008·Arquivos de neuro-psiquiatria·Marco Aurélio Lana-Peixoto
May 22, 2007·Journal of Neuroimmunology·Anu JacobBrian G Weinshenker
Jun 5, 2002·Current Opinion in Neurology·Douglas A Kerr, Harold Ayetey
May 23, 2002·American Journal of Physical Medicine & Rehabilitation·Tsui Fen YangRai Chi Chan
Nov 8, 2002·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Y Y El-SayedM L Druzin
Jul 29, 2000·Seminars in Pediatric Neurology·N F Schor

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Therapeutic Apheresis : Official Journal of the International Society for Apheresis and the Japanese Society for Apheresis
T Yamawaki, N Suzuki
© 2022 Meta ULC. All rights reserved