Three Years' Experience of a Novel Biosynthetic Cellulose Dressing in Burns

Advances in Wound Care
Matilda KarlssonMoustafa Elmasry

Abstract

Objective: The use of porcine xenograft (PX) is widely spread in burn care. However, it may cause immunologic responses and other ethical and cultural considerations in different cultures. Therefore, there is a need for alternatives. The aim of this work is to test a novel biosynthetic cellulose dressing (Epiprotect®) on burn patients. Approach: Charts from 38 patients with superficial burns (SBs) (n = 18) or excised burns (n = 20) that got biosynthetic cellulose dressing instead of PX at a national burn center during 3 years were reviewed. Time to healing, length of stay, and wound infection were extracted from the medical records. Results: SBs hospitalization time was 11 days comparable to PXs reported by others. In the excised group, median duration of hospital stay was 35 days. Time to healing was 28 days. Seven wound infections were confirmed in the superficial group (39%) and 11 infections in the excised group (61%). Patients with superficial wounds reported pain relief on application. Innovation: A dressing (17 × 21 cm) consisting of biosynthetic cellulose replacing PX. Conclusion: Outcome of treatment of SBs or temporary coverage of excised deep burns with biosynthetic cellulose is comparable to treatment with PX. Howev...Continue Reading

References

Apr 1, 1979·Plastic and Reconstructive Surgery·N M BreachA Yiacoumettis
Apr 1, 1976·The Journal of Trauma·M AronoffD L Simon
Jan 1, 1990·Applied Biochemistry and Biotechnology·J D FontanaL F Farah
May 1, 1973·Archives of Surgery·R E SalisburyB A Pruitt
Jun 9, 2004·Lancet·David N Herndon, Ronald G Tompkins
Aug 17, 2004·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·Jay A Fishman, Clive Patience
Oct 12, 2004·Burns : Journal of the International Society for Burn Injuries·Tor ChiuAndrew Burd
Jul 19, 2005·Clinics in Dermatology·Tor Chiu, Andrew Burd
Aug 16, 2005·Biomaterials·Wojciech CzajaR Malcolm Brown
Nov 10, 2005·Journal of Biomedical Materials Research. Part a·Gisela HeleniusBo Risberg
Mar 3, 2007·Burns : Journal of the International Society for Burn Injuries·Xiangsheng FengQiuhe Wu
Mar 14, 2007·Colloids and Surfaces. B, Biointerfaces·Li-Ling TangAi-Hua Su
Jul 6, 2012·International Wound Journal·Sang Uk ParkDae Hwan Park
Sep 17, 2013·Biotechnology and Applied Biochemistry·Bhavna V Mohite, Satish V Patil
Dec 3, 2013·BMC Medical Ethics·Axelina ErikssonJacob Rosenberg
Dec 19, 2015·Burns : Journal of the International Society for Burn Injuries·Roger Esteban-VivesJörg C Gerlach
Mar 23, 2017·Carbohydrate Polymers·Ayesha KhalidFazli Wahid
Jun 8, 2017·International Journal of Biological Macromolecules·Guilherme Fadel PichethRilton Alves de Freitas
Jul 19, 2017·International Journal of Biological Macromolecules·Zeng DiGuang Yang
Mar 22, 2018·Advances in Skin & Wound Care·Matilda KarlssonJohan Thorfinn

❮ Previous
Next ❯

Citations


❮ Previous
Next ❯

Methods Mentioned

BETA
xenografts
xenograft

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.