Three Years of Salvage IMRT for Prostate Cancer: Results of the Montpellier Cancer Center.

ISRN Urology
Olivier RiouD Azria

Abstract

Background. To assess the feasibility of salvage intensity-modulated radiation Therapy (IMRT) and to examine clinical outcome. Patients and Methods. 57 patients were treated with salvage IMRT to the prostate bed in our center from January, 2007, to February, 2010. The mean prescription dose was 68 Gy in 34 fractions. Forty-four patients received concomitant androgen deprivation. Results. Doses to organs at risk were low without altering target volume coverage. Salvage IMRT was feasible without any grade 3 or 4 acute gastrointestinal or urinary toxicity. With a median follow-up of 21 months, one grade 2 urinary and 1 grade ≥2 rectal late toxicities were reported. Biological relapse-free survival was 96.5% (2.3% (1/44) relapsed with androgen suppression and 7.7% (1/13) without). Conclusion. Salvage IMRT is feasible and results in low acute and chronic side-effects. Longer follow-up is warranted to draw conclusions in terms of oncologic control.

References

Sep 7, 2000·International Journal of Radiation Oncology, Biology, Physics·M S AnscherR Dodge
Jun 22, 2001·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·J Camilleri-Brennan, R J Steele
Aug 17, 2002·International Journal of Radiation Oncology, Biology, Physics·Michael D BastaschE Brian Butler
Sep 18, 2003·Journal of the National Cancer Institute·Anthony V D'AmicoMing-Hui Chen
Jul 13, 2004·The New England Journal of Medicine·Anthony V D'AmicoWilliam J Catalona
Jun 7, 2005·International Journal of Radiation Oncology, Biology, Physics·Mariana GuerreroBeth Erickson
Jul 28, 2005·JAMA : the Journal of the American Medical Association·Stephen J FreedlandAlan W Partin
Aug 16, 2005·Lancet·Michel BollaUNKNOWN European Organization for Research and Treatment of Cancer
Nov 16, 2006·JAMA : the Journal of the American Medical Association·Ian M ThompsonE David Crawford
Jan 16, 2007·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Gert O De MeerleerWilfried J De Neve
Mar 16, 2007·Clinical Oncology : a Journal of the Royal College of Radiologists·C ParkerUNKNOWN RADICALS Trial Management Group
Apr 10, 2007·International Journal of Radiation Oncology, Biology, Physics·Mary FengHoward M Sandler
May 2, 2007·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Stephen J FreedlandAlan W Partin
May 22, 2007·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Andrew J StephensonAlan Pollack
Aug 21, 2007·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Philip PoortmansUNKNOWN EORTC Radiation Oncology Group
Oct 9, 2007·European Urology·Axel HeidenreichUNKNOWN European Association of Urology
Oct 13, 2007·Cancer radiothérapie : journal de la Société française de radiothérapie oncologique·M BollaUNKNOWN au nom des groupes génito-urinaire et radiothérapie de l'EORTC
Oct 24, 2007·European Urology·Hendrik Van Poppel, Steven Joniau
Jun 3, 2008·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Mark A SidhomKeen-Hun Tai
Jun 6, 2008·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Ajay SandhuArno Mundt
Aug 23, 2008·International Journal of Radiation Oncology, Biology, Physics·Abrahim Al-MamganiJoos V Lebesque
Sep 6, 2008·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Gert De MeerleerWilfried De Neve
Oct 29, 2008·International Journal of Radiation Oncology, Biology, Physics·David Pasquier, Charles Ballereau
Jan 30, 2009·Medical Physics·Cedric X YuMichelle Svatos
Feb 28, 2009·Cancer radiothérapie : journal de la Société française de radiothérapie oncologique·D AzriaP Fenoglietto
Apr 28, 2009·International Journal of Radiation Oncology, Biology, Physics·Jeff M MichalskiCynthia Ménard
May 13, 2009·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Ian M ThompsonEric A Klein
Aug 4, 2009·Medical Dosimetry : Official Journal of the American Association of Medical Dosimetrists·Bridget F KoontzJames R Oleson
Sep 22, 2009·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Filippo AlongiNadia Di Muzio
Sep 25, 2009·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·Dirk BottkeThomas Wiegel
Oct 6, 2009·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Ayal A AizerRichard E Peschel
Oct 28, 2009·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Jennifer Y WoAnthony V D'Amico
Nov 27, 2009·International Journal of Radiation Oncology, Biology, Physics·Sameer K NathArno J Mundt
Dec 17, 2009·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Christopher ParkerMatthew R Sydes
Mar 11, 2010·Current Opinion in Urology·Robert L Grubb, Adam S Kibel
May 25, 2010·Progrès en urologie : journal de l'Association française d'urologie et de la Société française d'urologie·Y NeuzilletS Culine

❮ Previous
Next ❯

Citations

Sep 14, 2014·International Journal of Radiation Oncology, Biology, Physics·Sonja KatayamaKlaus Herfarth

❮ Previous
Next ❯

Software Mentioned

Eclipse

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Medical Dosimetry : Official Journal of the American Association of Medical Dosimetrists
Olivier RiouP Fenoglietto
International Journal of Radiation Oncology, Biology, Physics
Timothy N ShowalterL G Gomella
Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology
Tom BudihartoHendrik Van Poppel
Cancer radiothérapie : journal de la Société française de radiothérapie oncologique
S VieillotD Azria
© 2021 Meta ULC. All rights reserved