Threshold age and burn size associated with poor outcomes in the elderly after burn injury

Burns : Journal of the International Society for Burn Injuries
Marc G JeschkeSaeid Amini-Nik

Abstract

Elderly burn care represents a vast challenge. The elderly are one of the most susceptible populations to burn injuries, but also one of the fastest growing demographics, indicating a substantial increase in patient numbers in the near future. Despite the need and importance of elderly burn care, survival of elderly burn patients is poor. Additionally, little is known about the responses of elderly patients after burn. One central question that has not been answered is what age defines an elderly patient. The current study was conducted to determine whether there is a cut-off age for elderly burn patients that is correlated with an increased risk for mortality and to determine the burn size in modern burn care that is associated with increased mortality. To answer these questions, we applied appropriate statistical analyses to the Ross Tilley Burn Centre and the Inflammatory and Host Response to Injury databases. We could not find a clear cut-off age that differentiates or predicts between survival and death. Risk of death increased linearly with increasing age. Additionally, we found that the LD50 decreases from 45% total body surface area (TBSA) to 25% TBSA from the age of 55 years to the age of 70 years, indicating that even...Continue Reading

References

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Jul 5, 2006·Journal of Burn Care & Research : Official Publication of the American Burn Association·Matthew B KleinUNKNOWN Inflammation and the Host Response to Injury Investigators
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May 17, 2011·Burns : Journal of the International Society for Burn Injuries·Claudia R AlbornozIside Bravo
Jul 27, 2011·PloS One·Marc G JeschkeDavid N Herndon
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May 20, 2015·Burns : Journal of the International Society for Burn Injuries·Christopher WearnNaiem Moiemen

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Citations

Sep 9, 2016·Journal of Burn Care & Research : Official Publication of the American Burn Association·Christopher R BurkeD Michael McMullan
Mar 30, 2018·International Journal of Molecular Sciences·Alia SadiqSaeid Amini-Nik
Jul 28, 2019·Journal of Tissue Engineering and Regenerative Medicine·Nan ChengSaeid Amini-Nik
Dec 14, 2019·PloS One·Stephanie C DreckmannMarc G Jeschke
Jul 15, 2018·Stem Cell Research & Therapy·Nazihah BakhtyarSaeid Amini-Nik
Jul 3, 2020·International Journal of Molecular Sciences·Margarita EllosoMark G Jeschke
Oct 9, 2020·Journal of Burn Care & Research : Official Publication of the American Burn Association·Soman SenDavid Greenhalgh
Nov 28, 2020·Inflammation Research : Official Journal of the European Histamine Research Society ... [et Al.]·Benu GeorgeNitish Bhatia
Oct 31, 2020·Burns and Trauma·Harold GoeiUNKNOWN Dutch Burn Repository group
Dec 29, 2020·Burns : Journal of the International Society for Burn Injuries·Mizue MatsuoMasayuki Kamochi
May 18, 2021·Ageing Research Reviews·Maryam Mahjoob, Ursula Stochaj
Aug 4, 2021·Critical Care Nursing Clinics of North America·Mary G CareyMackenzie White
Jan 23, 2021·Shock·Marisa E LuckMashkoor A Choudhry

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