Thrombectomy in Childhood Stroke

Journal of the American Heart Association
Peter B SpornsMoritz Wildgruber

Abstract

Background Several randomized trials have shown the efficacy of thrombectomy for large intracranial vessel occlusions in adults. However, the safety and efficacy of thrombectomy in children are unknown. We aimed to investigate the feasibility and outcome of thrombectomy in pediatric patients. Methods and Results We performed a retrospective analysis of all children (<18 years of age) who presented with large-vessel occlusion and were treated with mechanical thrombectomy at 3 German tertiary-care stroke centers. Interventional results and clinical outcomes were assessed using the Pediatric National Institutes of Health Stroke Scale at 24 hours and on day 7 after thrombectomy as well as after 3 months (modified Rankin Scale). After screening of local registries for all performed thrombectomies, 12 children were included. Median Pediatric National Institutes of Health Stroke Scale score on admission was 12.5 (interquartile range 8.0-21.5). Angiographic outcomes for thrombectomy were good in all patients (6×modified Treatment in Cerebral Infarction Score 3, 6×modified Treatment in Cerebral Infarction Score 2b). Moreover, most patients showed an improvement of neurological outcome after thrombectomy with a median Pediatric National ...Continue Reading

References

Nov 30, 2007·The New England Journal of Medicine·David J Brenner, Eric J Hall
May 9, 2009·Lancet Neurology·Catherine Amlie-LefondUNKNOWN International Pediatric Stroke Study
Dec 18, 2014·The New England Journal of Medicine·Olvert A BerkhemerUNKNOWN MR CLEAN Investigators
Jan 24, 2015·Stroke; a Journal of Cerebral Circulation·Michael J RivkinCatherine Amlie-Lefond
Feb 12, 2015·The New England Journal of Medicine·Mayank GoyalUNKNOWN ESCAPE Trial Investigators
Apr 18, 2015·The New England Journal of Medicine·Tudor G JovinUNKNOWN REVASCAT Trial Investigators
May 27, 2017·Stroke; a Journal of Cerebral Circulation·Laurence TaboneManoelle Kossorotoff
Dec 24, 2017·Journal of Neuroradiology. Journal De Neuroradiologie·Manuel CappellariElisa Francesca Maria Ciceri
Apr 22, 2018·Annals of Neurology·Sandra BigiMaja Steinlin

❮ Previous
Next ❯

Citations

Nov 17, 2019·Paediatric Anaesthesia·Christa MorrisonTim Liversedge
Dec 10, 2019·Current Opinion in Neurology·Nicola D Fearn, Mark T Mackay
Jan 18, 2020·Stroke; a Journal of Cerebral Circulation·Peter B SpornsAndré Kemmling
Mar 3, 2020·Stroke; a Journal of Cerebral Circulation·Peter B SpornsUNKNOWN Save ChildS Investigators
Sep 12, 2020·Stroke; a Journal of Cerebral Circulation·Peter B Sporns, Marios Psychogios
Mar 16, 2021·Stroke; a Journal of Cerebral Circulation·Megan BarryUNKNOWN Thrombolysis in Pediatric Stroke (TIPSTER) Investigators*
Apr 3, 2021·Therapeutic Advances in Neurological Disorders·Peter B SpornsMarios Psychogios
Jun 27, 2021·Scientific Reports·Martin OlivieriLucia Gerstl
Jun 29, 2021·Journal of the American College of Emergency Physicians Open·Daniel KempleAlyse Stolting
Aug 1, 2021·The Lancet Child & Adolescent Health·Peter B SpornsMoritz Wildgruber
Aug 29, 2021·European Journal of Paediatric Neurology : EJPN : Official Journal of the European Paediatric Neurology Society·Melissa L HutchinsonRebecca N Ichord

❮ Previous
Next ❯

Methods Mentioned

BETA
dissection

Software Mentioned

Siemens

Related Concepts

Related Feeds

Brain Ischemia

Brain ischemia is a condition in which there is insufficient blood flow to the brain to meet metabolic demand. Discover the latest research on brain ischemia here.

Related Papers

Interventional Neuroradiology : Journal of Peritherapeutic Neuroradiology, Surgical Procedures and Related Neurosciences
Marius Georg KaschnerBernd Turowski
Interventional Neuroradiology : Journal of Peritherapeutic Neuroradiology, Surgical Procedures and Related Neurosciences
Pierre De MariniBenjamin Gory
© 2022 Meta ULC. All rights reserved