PMID: 8465516Jan 1, 1993Paper

Thrombendarteriitis pulmonalis carcinomatosa Ceelen: an immunohistological investigation

Virchows Archiv. A, Pathological Anatomy and Histopathology
W Bohle, H E Schaefer

Abstract

A 65-year-old woman died in sudden right heart failure caused by thrombendarteriitis pulmonalis carcinomatosa Ceelen 16 months after resection of a rectal carcinoma. Autopsy disclosed a complex picture of multiple tumour cell emboli in small pulmonary arteries associated with local thrombosis and thrombus-associated vessel wall reaction. This was characterized by movement of medial muscle cells into the thrombus. In addition, affected vessels showed a prominent perivascular tumour-related infiltration by lymphocytes which are identified immunohistochemically as CD3-reactive T-cells.

References

Jul 15, 1987·International Journal of Cancer. Journal International Du Cancer·S von KleistC Wittekind
Feb 20, 1986·The New England Journal of Medicine·R Ross

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