Abstract
Abnormalities of blood system often occur several days before acute kidney injury (AKI) in patients with heat stroke (HS). We aimed to investigate the prevalence and prognostic value of the early hematological markers in patients with AKI induced by HS. In a retrospective cohort study, we analyzed the case records of 176 patients with HS and evaluated the hematological markers for early prediction and risk classification in the patients with AKI. Of 176, 103 (58%) HS cases developed AKI, and men comprised more than half (75%) of the sample population. The nadir platelet count significantly correlated with the levels of peak serum creatinine (r = -0.608, p < 0.01) and blood urea nitrogen (r = -0.546, p < 0.01), and the length of hospital stay (r = -0.393, p < 0.01). The areas under the receiver operating characteristic curves (AU-ROC) indicated the prognostic accuracy of hematological markers, AU-ROC was significantly higher with the nadir platelet count than that with the admission platelet count (AU-ROC of the nadir platelet: 0.73; 95% CI: 0.67-0.82; vs. AU-ROC of the admission platelet: 0.67; 95% CI: 0.59-0.75; p < 0.01). Multiple logistic regression results indicated that the nadir platelet count (adjusted ORs: 37.92; 95% CI...Continue Reading
References
Jan 1, 1992·Renal Failure·D LumlertgulM Keoplung
Mar 1, 1973·Southern Medical Journal·S F RajuJ D Bower
Jul 1, 1995·Renal Failure·G WoodrowJ H Turney
Nov 14, 1997·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·F C YuY F Lin
May 6, 1999·Intensive Care Medicine·Y IkedaK Taki
Aug 3, 1999·American Journal of Preventive Medicine·J C Semenza
Jun 21, 2002·The New England Journal of Medicine·Abderrezak Bouchama, James P Knochel
Jan 13, 2004·Intensive Care Medicine·Abderrezak Bouchama
Sep 20, 2006·The Journal of Emergency Medicine·Melanie DeutschStephanos Hadziyannis
Nov 14, 2006·The American Journal of Emergency Medicine·Alexandre Leite de SouzaAntonio C Seguro
Jul 21, 2007·Brain Research·Virginie MichelFrédéric Canini
Mar 6, 2010·Cytokine·Zhang PengHuang Chen
Apr 27, 2010·PLoS Pathogens·Roberto G PoznerRicardo M Gómez
Jun 29, 2010·Thrombosis Research·Outi LaineLotta Joutsi-Korhonen
Nov 8, 2011·Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·Satoshi YamashitaMakoto Uchino
May 15, 2013·Archives of Medical Science : AMS·Przemysław PuzKrzysztof Ziaja
Jul 5, 2013·American Journal of Physiology. Renal Physiology·Naushad A JungleeJamie H Macdonald
Sep 11, 2013·Journal of the Formosan Medical Association = Taiwan Yi Zhi·Kai-Li LeeChiang-Shan Niu
Aug 5, 2014·Renal Failure·Heng FanFu-chun Song
Citations
Feb 28, 2019·Platelets·Ming WuYong-Wen Feng
Aug 27, 2019·The Journal of International Medical Research·Guo-Dong ChenJian-Hua Zhu
Apr 18, 2020·Platelets·Jaesik ParkMin Suk Chae
Jul 19, 2020·Diseases·Charat ThongprayoonWisit Kaewput
Aug 21, 2020·Annals of Hematology·Robert StuverBruno Bockorny
Aug 23, 2020·Journal of Clinical Medicine·Joana GameiroJosé António Lopes
Aug 8, 2019·Annals of Intensive Care·Joana Gameiro, José António Lopes
Mar 15, 2020·Nutrients·Puqiao LianSoheil Varasteh
Nov 18, 2020·International Journal of Clinical Practice·Wisit KaewputWisit Cheungpasitporn
May 12, 2020·The American Journal of Emergency Medicine·Ling XingQiu-Mei Cao
Jun 8, 2021·Frontiers in Medicine·Ming WuZhifeng Liu