Thromboembolic Disease After Orthopedic Trauma

The Orthopedic Clinics of North America
Paul S Whiting, A Alex Jahangir

Abstract

Orthopedic trauma results in systemic physiologic changes that predispose patients to venous thromboembolism (VTE). In the absence of prophylaxis, VTE incidence may be as high as 60%. Mechanical and pharmacologic thromboprophylaxis are effective in decreasing rates of VTE. Combined mechanical and pharmacologic thromboprophylaxis is more efficacious for decreasing VTE incidence than either regimen independently. If pharmacologic thromboprophylaxis is contraindicated, mechanical prophylaxis should be used. Patients with isolated lower extremity fractures who are ambulatory, or those with isolated upper extremity trauma, do not require pharmacologic prophylaxis in the absence of other VTE risk factors.

References

Jun 1, 1990·The Journal of Trauma·K F O'Malley, S E Ross
Dec 15, 1994·The New England Journal of Medicine·W H GeertsJ P Szalai
Jun 24, 2005·The Journal of Bone and Joint Surgery. British Volume·J P StannardJ E Alonso
Feb 3, 2006·The Journal of Bone and Joint Surgery. American Volume·James P StannardJorge E Alonso
Apr 7, 2007·The Journal of Trauma·Avery B NathensRonald V Maier
Oct 25, 2007·The Journal of Bone and Joint Surgery. British Volume·S PatilA C W Hui
Mar 5, 2009·The Journal of Bone and Joint Surgery. British Volume·D P GoelR Gray
Apr 25, 2009·Journal of Orthopaedic Trauma·Gerard P SlobogeanPeter J O'Brien
Jul 18, 2009·Injury·Thomas PaffrathUNKNOWN Trauma Registry of DGU
Dec 27, 2011·The Journal of Foot and Ankle Surgery : Official Publication of the American College of Foot and Ankle Surgeons·Naohiro ShibuyaDaniel C Jupiter
Mar 14, 2012·Annals of Internal Medicine·Diana M SobierajC Michael White
Aug 14, 2013·The Journal of Trauma and Acute Care Surgery·Gordon M RihaMartin A Schreiber
Jan 1, 2014·Journal of Orthopaedic Trauma·Yelena BogdanCory Collinge
Jun 28, 2014·Orthopedics·Jakub GodzikMichael P Kelly
Dec 30, 2014·The Journal of the American Academy of Orthopaedic Surgeons·John A ScolaroNathan A Wigner

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Citations

Feb 9, 2018·Current Sports Medicine Reports·Jennifer Oberstar, Chrystian Pereira
May 28, 2019·Journal of Orthopaedic Trauma·Jesse DashePaul Tornetta
Jul 5, 2017·Progress in Rehabilitation Medicine·Kouji TsudaJun Kitagawa
Apr 27, 2021·The Journal of Foot and Ankle Surgery : Official Publication of the American College of Foot and Ankle Surgeons·Joseph V VillarrealDaniel C Jupiter

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