Sep 1, 1977

Thromboembolism in Hageman trait

American Journal of Clinical Pathology
R A McPherson


The case of a patient with severe deficiency of Hageman factor (factor XII) in whom a thrombus embolized to arteries in a lower extremity is described. In addition to its action in intiating blood clotting through the intrinsic pathway, Hageman factor can influence kinin generation, fibrinolysis, and activation of complement. While individuals with Hageman factor deficiency have no hemorrhagic disorder, this case emphasizes the role factor XII may normally assume in clot dissolution.

  • References
  • Citations


  • We're still populating references for this paper, please check back later.
  • References
  • Citations


  • This paper may not have been cited yet.

Mentioned in this Paper

Biochemical Pathway
Arterial System
Factor XII Deficiency
Blood Coagulation Disorders
Assay of Fibrinolysis
Blood Clot

Related Feeds

Blood Clotting Disorders

Thrombophilia includes conditions with increased tendency for excessive blood clotting. Blood clotting occurs when the body has insufficient amounts of specialized proteins that make blood clot and stop bleeding. Here is the latest research on blood clotting disorders.