PMID: 11917970Mar 29, 2002Paper

Thrombolysis for acute ischemic stroke: the problem of consent

Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology
A CicconeItalian Neurological Society's Study Group for Bioethics and Palliative Care in Neurology

Abstract

The physician who decides to administer a thrombolytic therapy to a patient with acute stroke, has to consider both the results of randomized controlled trials, a complex matter itself, and problems related to consent, with its deontological and legal aspects, in the difficult contest of the emergency situations and acute stroke care. Although the analysis of studies on thrombolysis in medical literature has been ample and may be redundant, the latter aspect, i.e. that of how to cope with the problem of consent, has never been treated adequately. The problem of consent is particularly important and delicate in Italy and in most countries of the European Union, where thrombolytic therapy can be used only off label or within experimental studies. This document aims to provide the tools needed to overcome the gap between the generic indication for thrombolytic therapy in acute stroke, coming from clinical studies, and its effective use.

Citations

Dec 22, 2012·Evidence-based Complementary and Alternative Medicine : ECAM·Jaeho OhMichung Yoon
Dec 22, 2010·Neurologic Clinics·Teresa Lim, Deborah B Marin
Oct 16, 2016·Emergency Medicine Clinics of North America·Matthew S Siket
Sep 11, 2013·Journal of Intensive Care Medicine·Fred Rincon, Kiwon Lee
Nov 3, 2021·Acta Neurologica Scandinavica·Peter AppelrosMia Svantesson

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