Thromboprophylaxis in hip arthroplasty. Dextran with graded compression or preoperative dextran compared in 150 patients.

Acta Orthopaedica Scandinavica
H FredinU Nyman

Abstract

Totally, 150 patients, subjected to total hip arthroplasty, were randomly allocated into three prophylactic groups with either conventional dextran alone or with additional graded compression stockings or with additional preoperative administration of dextran. The overall frequency of deep venous thrombosis (DVT), as studied by radioactive fibrinogen uptake test and ascending phlebography of the operated on thigh was in the conventional dextran group 46 percent, the additional stockinged group 30 percent, and in the additional preoperative dextran group 52 percent. In the stockinged group, there was a lower frequency of DVT in the nonoperated on leg as well as, on an average, about 350 mL less peroperative bleeding as compared with the other two groups. No adverse reaction occurred from dextran administration. Increased and prolonged postoperative administration of dextran decrease the number of femoral DVTs.

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Citations

Nov 26, 2010·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·D MarslandS L Kates
Sep 30, 1998·The British Journal of Surgery·C J WildinP J Gregg
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Nov 6, 2018·The Cochrane Database of Systematic Reviews·Ashwin SachdevaTimothy Lees
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Aug 1, 1994·The Journal of Bone and Joint Surgery. American Volume·J R Lieberman, W H Geerts
Dec 25, 2013·Journal of Orthopaedic Surgery·Nimesh PatelJames Gibbs

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