Thrombosis and coagulopathy in COVID-19: An illustrated review.

Research and Practice in Thrombosis and Haemostasis
Marcel Levi, Beverley J Hunt

Abstract

This illustrated review discusses the haemostatic changes seen in patients with severe coronavirus disease 2019 (COVID-19) infection and their possible causes. We discuss the crosstalk between inflammation and coagulation resulting in high levels of acute-phase proteins, very high levels of D-dimers, and absence of disseminated intravascular coagulation seen in patients with severe COVID-19. There appear to be high rates of venous thromboembolism and also, what has been poorly described before in acute lung injury, a high rate of pulmonary immunothrombosis (thrombosis secondary to inflammation).

References

Aug 19, 1999·The New England Journal of Medicine·M Levi, H Ten Cate
Jun 9, 2004·Circulation·Marcel LeviHarry R Büller
Jan 17, 2015·Seminars in Thrombosis and Hemostasis·Kochawan Boonyawat, Mark A Crowther
Jun 3, 2016·Nature Reviews. Disease Primers·Satoshi GandoCheng-Hock Toh
May 31, 2018·Journal of Thrombosis and Haemostasis : JTH·K SuzukiUNKNOWN Subcommittee on Disseminated Intravascular Coagulation
Feb 20, 2020·Journal of Thrombosis and Haemostasis : JTH·Ning TangZiyong Sun
Feb 29, 2020·The New England Journal of Medicine·Wei-Jie GuanUNKNOWN China Medical Treatment Expert Group for Covid-19
Mar 21, 2020·Lancet·Puja MehtaUNKNOWN HLH Across Speciality Collaboration, UK
Apr 28, 2020·Journal of Thrombosis and Haemostasis : JTH·Jecko ThachilToshiaki Iba

❮ Previous
Next ❯

Citations

Sep 4, 2020·Journal of Thrombosis and Thrombolysis·Ton Lisman, Jecko Thachil
Nov 21, 2020·Haemophilia : the Official Journal of the World Federation of Hemophilia·Steven W PipeUNKNOWN Coagulation Products Safety, Supply and Access (CPSSA) Committee of the World Federation of Hemophilia
Nov 27, 2020·Medical Hypotheses·Xiyuan BaiEdward D Chan
Feb 13, 2021·Journal of Clinical Medicine·Tanja FalterMartin F Sprinzl
Nov 3, 2020·Research and Practice in Thrombosis and Haemostasis·Dre'Von A Dobson, Alisa S Wolberg
Feb 5, 2021·Research and Practice in Thrombosis and Haemostasis·Mary Cushman
Feb 5, 2021·Research and Practice in Thrombosis and Haemostasis·Fien A von MeijenfeldtTon Lisman
Nov 3, 2020·Research and Practice in Thrombosis and Haemostasis·Nithita NanthatantiSomnuek Sungkanuparph
Feb 10, 2021·Blood Advances·Fien A von MeijenfeldtTon Lisman
Mar 19, 2021·Research and Practice in Thrombosis and Haemostasis·Marieke J H A KruipUNKNOWN Dutch COVID Thrombosis Coalition study group
Apr 8, 2021·Nature Reviews. Immunology·Aldo BonaventuraAntonio Abbate
May 6, 2021·Memórias do Instituto Oswaldo Cruz·Rubens Carmo Costa-FilhoJosé Paulo Gagliardi Leite
Jun 7, 2021·Vascular Pharmacology·Laurent BertolettiPatrick Mismetti
Jul 22, 2021·International Journal of Laboratory Hematology·Katrien M J Devreese

❮ Previous
Next ❯

Related Concepts

Related Feeds

Blood Clotting Disorders

Thrombophilia includes conditions with increased tendency for excessive blood clotting. Blood clotting occurs when the body has insufficient amounts of specialized proteins that make blood clot and stop bleeding. Here is the latest research on blood clotting disorders.