PMID: 19927759Nov 26, 2009Paper

Thrombosis in inflammatory bowel disease: mechanisms and risk factors

La Tunisie médicale
Leila MouelhiTaoufik Najjar

Abstract

Thromboembolic manifestations are frequent in patients with inflammatory bowel disease. To explaim the mechanisms of thromboembolic manifestations in inflammatory bowel disease. Literature review. Risk factors of thrombosis in inflammatory bowel disease are acquired or genetic. The most important factors are thrombocytosis, increased of activation of platelets and hyperhomocysteinemia. Other factors such factor V leiden, antithrombin III and antiphospholipid antibodies are observed in inflammatory bowel disease patients but not always correlated with thromboembolic manifestations. The mechanisms of thrombosis in inflammatory bowel disease are complex are intricate.

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Antiphospholipid Syndrome

Antiphospholipid syndrome or antiphospholipid antibody syndrome (APS or APLS), is an autoimmune, hypercoagulable state caused by the presence of antibodies directed against phospholipids.

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