Thrombotic complications resulting from hypercoagulable states in chronic hemodialysis vascular access

Journal of the American College of Surgeons
C J LeSarM R Smith

Abstract

Vascular access-related complications are an important cause of morbidity, and they account for 14% to 17% of dialysis patients' hospitalizations with an annual cost in the United States of approximately $1 billion. Previous studies have related the major predisposing factor of thrombotic complications to stenosis of the graft anastomosis. Several recent reports suggest that antiphospholipid antibodies may cause frequent thrombotic complications. The broad spectrum of diseases that cause hypercoagulable states has not been correlated with frequent PTFE graft thrombosis. A retrospective case series study was performed to determine the frequency of hypercoagulable states in dialysis patients who had repeated thrombotic complications of their PTFE grafts. Between May 1996 and June 1998, 91 operations were performed on 34 patients with end-stage renal disease. All arteriovenous fistulas were created with PTFE grafts and placed by a single surgeon. All patients were evaluated at operation for anastomotic stenosis, and the majority of patients were studied for hypercoagulable states. Patients with a documented hypercoagulable state were considered for warfarin therapy. Twenty-two individuals (64.7%) developed 67 thrombotic complicati...Continue Reading

References

Aug 15, 1992·Annals of Internal Medicine·M H Rosove, P M Brewer
May 15, 1986·The New England Journal of Medicine·L H Clouse, P C Comp
Aug 1, 1985·Annals of Surgery·S B PalderN L Tilney
Sep 6, 1984·The New England Journal of Medicine·S Wessler, S N Gitel
Dec 13, 1984·The New England Journal of Medicine·V Parsonnet
Aug 1, 1995·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·K CulpM Rothstein
Aug 1, 1995·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·R PrakashW N Suki
Apr 13, 1995·The New England Journal of Medicine·M A KhamashtaG R Hughes
Jan 1, 1994·Seminars in Thrombosis and Hemostasis·R L Bick, W F Baker
Sep 1, 1994·The Journal of Clinical Investigation·B Dahlbäck
Feb 24, 1994·The New England Journal of Medicine·P J Svensson, B Dahlbäck
May 1, 1993·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·D W Windus
Jan 1, 1997·Gynecologic and Obstetric Investigation·M UszyńskiE Zekanowska
Aug 1, 1997·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation

❮ Previous
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Citations

Mar 26, 2008·Journal of Thrombosis and Thrombolysis·Ramazan DanisAdil Polat
Dec 3, 2008·Clinical Reviews in Allergy & Immunology·Maria G Tektonidou
Aug 8, 2002·Kidney International·Chike M NzerueE Nigel Harris
Mar 11, 2004·Seminars in Vascular Surgery·Christopher J AbularrageSubodh Arora
Nov 4, 2010·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Felix YangSam Hanon
May 16, 2003·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Volker Mickley
Nov 2, 2012·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Catherine M ClaseDeborah L Zimmerman
Sep 12, 2009·Seminars in Dialysis·Rachel M Holden, Catherine M Clase
Oct 26, 2007·American Journal of Nephrology·Sandra CrikisVicki Levidiotis
Feb 20, 2009·Journal of the American Society of Nephrology : JASN·Nita A LimdiMichael Allon
Nov 16, 2007·Clinical Journal of the American Society of Nephrology : CJASN·Rachel M HoldenAndrew G Day
Feb 16, 2013·Clinical Journal of the American Society of Nephrology : CJASN·Birgitta SalmelaRiitta Lassila
May 31, 2002·Expert Opinion on Investigational Drugs·Robert IsomJai Radhakrishnan
Jan 30, 2015·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·S BrauneF Jung
Feb 3, 2015·Hämostaseologie·A BauerU Nowak-Göttl
Oct 10, 2007·Hemodialysis International·Hadim AkogluCetin Turgan
Oct 11, 2015·Journal of the American Society of Nephrology : JASN·Chih-Cheng WuDer-Cherng Tarng
Mar 5, 2005·Journal of Cardiothoracic and Vascular Anesthesia·Rosaleen ChunDavid Royston
Aug 2, 2006·Rheumatic Diseases Clinics of North America·Mary-Carmen Amigo
Nov 22, 2005·European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery·C P Gibbons
Feb 22, 2017·Néphrologie & thérapeutique·Pierre DelanayePatrizio Lancellotti
Jun 27, 2002·Advances in Renal Replacement Therapy·Jocelyn S GarlandRobert M Lindsay
Dec 28, 2007·Clinical and Applied Thrombosis/hemostasis : Official Journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis·Samer E ElChoufaniArthur P Bode
Jun 7, 2018·The Annals of Pharmacotherapy·Joseph H SchaferBritta A Staubes
Apr 21, 2005·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Füsun GültekinHafize Sezer
Feb 25, 2005·Journal of the American Society of Nephrology : JASN·Greg A KnollMarc A Rodger
Nov 25, 2006·Hematology·Paula L Bockenstedt
Dec 8, 2015·Clinical Hemorheology and Microcirculation·S BrauneF Jung
Nov 26, 2002·Hematology·Julie HambletonMarcel Levi
Nov 10, 2000·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·J H SmitsT J Rabelink
Dec 9, 2016·Journal of Nephrology·Massimiliano MiglioriVincenzo Panichi
Jun 12, 2020·Hemodialysis International·Paul R J AmesFabrizio Gentile
Dec 19, 2020·Clinical Hemorheology and Microcirculation·A Krüger-GengeF Jung
Dec 3, 2002·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Rajiv SaranUNKNOWN Dialysis Outcomes and Practice Patterns Study
Aug 30, 2003·Journal of Vascular Surgery·Susan I O'sheaThomas L Ortel
Oct 16, 2004·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Vittorio E AndreucciFriedrich K Port
Feb 28, 2001·Journal of the American College of Surgeons·J L Cronenwett
Jul 8, 2008·European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery·S K KakkosM M Scully

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