PMID: 656348Jun 1, 1978Paper

Thromboxane B2 in amniotic fluid before and during labour

British Journal of Obstetrics and Gynaecology
M D MitchellA C Turnbull

Abstract

Concentrations of thromboxane B2 (TXB2) have been measured in amniotic fluid obtained during late pregnancy and labour. Samples taken at amniocentesis contained significantly lower levels of TXB2 than samples taken by amniotomy for the induction of labour which in turn contained significantly less than when the same procedure was performed during labour. In the latter group there was no correlation between the degree of cervical dilatation and the concentration of TXB2. There was no correlation between gestational age and the concentration of TXB2 in amniotic fluid obtained at amniocentesis whereas there was a significant correlation (P less than 0.025) between these parameters when fluid was taken by amniotomy before labour. It is suggested that the relative activities of the enzymes responsible for the conversion of prostaglandin endoperoxides to prostaglandins, thromboxane A2 and prostacyclin may be of great importance during parturition.

References

Jun 1, 1978·The Journal of Clinical Endocrinology and Metabolism·M D MitchellA C Turnbull
Feb 1, 1978·Clinical Endocrinology·M E MorgansS A Whitehouse
Dec 1, 1977·British Journal of Obstetrics and Gynaecology·M J KeirseA C Turnbull
Jan 1, 1977·British Journal of Obstetrics and Gynaecology·M D MitchellA C Turnbull
Aug 1, 1975·Proceedings of the National Academy of Sciences of the United States of America·M HambergB Samuelsson
Nov 1, 1973·The Journal of Obstetrics and Gynaecology of the British Commonwealth·M J Keirse, A C Turnbull
Feb 1, 1974·The Journal of Obstetrics and Gynaecology of the British Commonwealth·M J KeirseA C Turnbull
Apr 1, 1974·The Journal of Obstetrics and Gynaecology of the British Commonwealth·K HillierM P Embrey
Dec 1, 1966·The Journal of Obstetrics and Gynaecology of the British Commonwealth·S M Karim
Apr 1, 1967·The Journal of Obstetrics and Gynaecology of the British Commonwealth·S M Karim, J Devlin

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Citations

Sep 1, 1987·Prostaglandins·W A NoortM J Keirse
Apr 1, 1984·Prostaglandins, Leukotrienes, and Medicine·S ShaalaM Toppozada
Jan 1, 1985·British Journal of Obstetrics and Gynaecology·M Cvetkovic, O Ylikorkala
Mar 1, 1980·British Journal of Obstetrics and Gynaecology·D S BamfordK I Williams
Sep 1, 1993·Circulation·E A Meagher, G A FitzGerald
Aug 1, 1984·British Journal of Obstetrics and Gynaecology·K ReddiR H Philpott

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