Thrombus Length Estimation on Delayed Gadolinium-Enhanced T1

Stroke; a Journal of Cerebral Circulation
Shen-qiang YanMin Lou

Abstract

Previous studies revealed a close relationship between thrombus length and recanalization rate after intravenous thrombolysis (IVT). As a novel approach, we prospectively adjusted the order of sequence acquisition to obtain delayed gadolinium-enhanced T1 (dGE-T1) and thereby assess thrombus length on dGE-T1 to evaluate its predictive value for recanalization after IVT. We reviewed prospectively collected clinical and imaging data from acute ischemic stroke patients with middle cerebral artery occlusion who underwent multimodal magnetic resonance imaging before and 24 hours after IVT. Perfusion-weighted imaging was performed followed by conventional T1. We measured thrombus length on dGE-T1 and examined its association with middle cerebral artery recanalization. Of the included 74 patients, the median age was 66 years and 28 (37.8%) were women. Thrombus length was 8.18±4.56 mm on dGE-T1, which was an acceptable predictor for no recanalization (odds ratio, 1.196; 95% confidence interval, 1.015-1.409; P=0.033), with a receiver-operator characteristic of 0.732 (95% confidence interval, 0.619-0.845; P=0.001). The optimal cut-off point was identified at 6.77 mm, which yielded a sensitivity of 77.8%, a specificity of 57.9%, and an odd...Continue Reading

References

Oct 15, 2005·Stroke; a Journal of Cerebral Circulation·Kyung-Hee ChoDong-Wha Kang
Mar 12, 2011·Stroke; a Journal of Cerebral Circulation·David S LiebeskindJeffrey L Saver
Aug 27, 2011·Stroke; a Journal of Cerebral Circulation·Kazumi KimuraTakashi Inoue
May 25, 2013·Journal of Neurointerventional Surgery·Alex M MortimerMarcus D Bradley
Aug 8, 2013·Stroke; a Journal of Cerebral Circulation·Osama O ZaidatUNKNOWN STIR Thrombolysis in Cerebral Infarction (TICI) Task Force
Nov 21, 2013·Journal of Neuroimaging : Official Journal of the American Society of Neuroimaging·María Hernández-PérezAntoni Dávalos
Jun 12, 2014·Stroke; a Journal of Cerebral Circulation·Vladimir RohanJiri Ferda
Dec 18, 2014·The New England Journal of Medicine·Olvert A BerkhemerUNKNOWN MR CLEAN Investigators
Feb 12, 2015·The New England Journal of Medicine·Bruce C V CampbellUNKNOWN EXTEND-IA Investigators
Feb 12, 2015·The New England Journal of Medicine·Mayank GoyalUNKNOWN ESCAPE Trial Investigators
Apr 18, 2015·The New England Journal of Medicine·Jeffrey L SaverUNKNOWN SWIFT PRIME Investigators
Apr 18, 2015·The New England Journal of Medicine·Tudor G JovinUNKNOWN REVASCAT Trial Investigators
May 15, 2015·Neurology·Shreyansh ShahAmie W Hsia

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Citations

Nov 21, 2017·Journal of Neurointerventional Surgery·Ramanan GaneshanJochen B Fiebach
Jan 13, 2018·Stroke; a Journal of Cerebral Circulation·Heitor C AlvesUNKNOWN MR CLEAN trial investigators
Jan 16, 2016·Stroke; a Journal of Cerebral Circulation·Bruce C V Campbell
Apr 25, 2017·British Journal of Neurosurgery·Naif M AlotaibiVictor X D Yang
Aug 10, 2017·Expert Review of Cardiovascular Therapy·Gregory B WalkerTudor G Jovin
Nov 23, 2017·Scientific Reports·Jang-Hyun BaekJi Hoe Heo
Mar 10, 2017·Topics in Magnetic Resonance Imaging : TMRI·Johnny H Wong, Michael P Marks
Apr 13, 2018·Stroke; a Journal of Cerebral Circulation·Zhicai ChenMin Lou
Feb 23, 2020·Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·Shuang-Jiao HuangYan Kong
Feb 19, 2021·Scientific Reports·Robert T KlevenChristy K Holland

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