Thujaplicins from Thuja plicata as iron transport agents for Salmonella typhimurium.

Journal of Bacteriology
H A AkersE Garland

Abstract

Strains of Salmonella typhimurium which are unable to synthesize their normal iron transport agent, enterobactin, and which must be supported with an exogenous chelator (siderophore) on certain media, were used to examine various types of wood for the presence of chelators. Western red cedar wood, Thuja plicata, was observed to contain large amounts of three substances that in low concentration would serve as chelators for S. typhimurium. The chelators from T. plicata were characterized and found to be alpha-, beta-, and gamma-thujaplicin. Other planar cyclic alpha-hydroxyketones were examined, and several were found to function as chelators for S. typhimurium.

References

Nov 1, 1973·Canadian Journal of Microbiology·T J Trust, R W Coombs
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Mar 12, 1970·Biochemical and Biophysical Research Communications·J R Pollack, J B Neilands
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Sep 1, 1967·Journal of Medicinal Chemistry·S J Norton, E Sanders
Jul 1, 1947·Journal of the American Chemical Society·R ADAMSJ L JOHNSON

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Citations

Jan 1, 1988·FEMS Microbiology Immunology·J H BrockG J Kontoghiorghes
Aug 20, 2016·Biometals : an International Journal on the Role of Metal Ions in Biology, Biochemistry, and Medicine·Zhen JiangZhixiong Xie
May 1, 1983·Applied and Environmental Microbiology·H A Akers

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