Thymoma-associated multiorgan autoimmunity

BMJ Case Reports
Chien-Tzu HungMin-Shu Hsieh

Abstract

Thymoma-associated multiorgan autoimmunity is a relatively new term to describe the rare paraneoplastic syndrome that complicates thymoma, which can involve the thyroid, liver and intestine in addition to the skin. The pathology often indicates a graft-versus-host-like pattern commonly observed in recipients of an allogeneic haematopoietic cell transplant. We report a case of type B2 and B3 thymoma with invasion to the lung and pleura in a patient who presented with oral lichen planus and graft-versus-host-like erythroderma. The cutaneous lesions improved after complete resection of the thymoma in combination with systemic glucocorticoids, which was subsequently complicated by cytomegalovirus pneumonitis.

References

Apr 17, 2007·Journal of the American Academy of Dermatology·Akhil WadheraPeter J Lynch
Apr 13, 2010·Autoimmunity·A MarxP Ströbel
Nov 15, 2014·Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer·Benny Weksler, Binfeng Lu
Jun 17, 2015·The Journal of Dermatology·Sei-Ichiro MotegiOsamu Ishikawa
Sep 27, 2015·Autoimmunity Reviews·C BernardP Sève
Mar 29, 2016·European Journal of Dermatology : EJD·Minako NakayamaHidemi Nakagawa

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Citations

Sep 30, 2020·International Journal of Dermatology·Martí Pons BenaventDolores Ramón Quiles
May 8, 2021·The American Journal of the Medical Sciences·Zoe AlexakouAlexandra Alexopoulou

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Methods Mentioned

BETA
biopsy

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