Thymomas I: a clinicopathologic correlation of 250 cases with emphasis on the World Health Organization schema.

American Journal of Clinical Pathology
C A MoranS Suster

Abstract

We describe 250 cases of thymoma with emphasis on World Health Organization (WHO) histologic subtyping. The patients were 120 males and 130 females between the ages of 13 and 92 years. Surgical resection was performed, and histologic material was evaluated in every case. Macroscopically, the tumors varied in size from 3 to 20 cm in greatest diameter; about 12% were encapsulated, and about 88% were invasive tumors. A minimum of 5 sections of tumor was evaluated. Histologically, following the schema proposed by the WHO, 21.6% of thymomas were type A, 1.23% type B1, 3.2% type B2, and 9.2% type B3. More than 50% of tumors after subtyping fell into the mixed categories, which, in essence, diminishes the clinical impact of histologic subtyping over staging. The study herein described highlights that all thymomas had the potential to become invasive tumors.

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Citations

Jun 9, 2015·PET Clinics·Mie Holm Vilstrup, Drew A Torigian
Aug 6, 2014·Human Pathology·Annikka WeissferdtCesar A Moran
Dec 6, 2014·Case Reports in Oncological Medicine·Mamatha SiricillaRobert Avery
Aug 6, 2016·Ocular Immunology and Inflammation·Takenori InomataAkira Murakami
May 12, 2017·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Brett W CarterEdith M Marom
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May 23, 2020·Innovations : Technology and Techniques in Cardiothoracic and Vascular Surgery·Abbas El-Sayed Abbas
Feb 21, 2013·Journal of Thoracic Imaging·Edith M Marom
Jun 23, 2019·Current Treatment Options in Oncology·Elizabeth A LippnerTamiko R Katsumoto
Apr 24, 2018·Oncotarget·Giorgio SantoniRossana Berardi
Jun 24, 2015·Oncotarget·Chih-Chia LiangChun-Ming Chen
Mar 5, 2013·Diagnostic Cytopathology·Marc PusztaszeriJean-Claude Pache
Nov 11, 2014·Histopathology·Anna C GreenAndrew G Nicholson
Sep 25, 2018·American Journal of Clinical Pathology·Neda Kalhor, Cesar A Moran
Jun 21, 2021·Seminars in Diagnostic Pathology·Diana M Oramas, Cesar A Moran
Jun 18, 2021·Advances in Anatomic Pathology·Diana M Oramas, Cesar A Moran

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