PMID: 6106426May 1, 1980Paper

Thymus-endocrine interactions during ageing

Aktuelle Gerontologie
L PiantanelliN Fabris

Abstract

The hypotesis of the thymus acting as biological clock for ageing is revisited. On the basis of data on the endocrine action of the gland, the age-dependent involution of the thymus is postulated to play a fundamental role on the deterioration of the immunological as well as the endocrine functions. Data either on beta-adrenergic responsiveness to Isoproterenol or on hormonal balance, tested on animal model with different degree of thymus efficiency, support this hypothesis.

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