PMID: 11921503Mar 30, 2002Paper

Thyroid abnormalities in lithium-treated patients with bipolar affective disorder

The Journal of International Medical Research
A CayköylüR Cetinkaya

Abstract

The thyroid functions of 42 subjects with bipolar affective disorder receiving regular lithium therapy were analysed and their thyroid glands were examined by ultrasonography. Following the receipt of lithium therapy (duration 4-156 months), three subjects displayed subclinical hypothyroidism (7.1%), three subclinical hyperthyroidism (7.1%) and one hyperthyroidism (2.4%). Moreover, goitre was detected in 16 (38.1%) subjects. An increase in the conversion of free thyroxine (T4) to free tri-iodothyrosine (T3), which is an indication of mild thyroid dysfunction, was identified in 20 (47.6%) subjects, and was mostly seen in male subjects under 40 years of age and in those having weight gain. In conclusion, some thyroid dysfunctions were observed in the patients treated with lithium.

References

Feb 1, 1978·The Journal of Clinical Endocrinology and Metabolism·S T BigosF Maloof
Mar 1, 1991·Acta Psychiatrica Scandinavica·A BocchettaM Del Zompo
Jul 1, 1990·International Clinical Psychopharmacology·Y Chen, T Silverstone
Nov 1, 1989·Archives of Neurology·J I IsojärviV V Myllylä
Jul 1, 1970·The Journal of Clinical Investigation·S C BerensJ Wolff
Nov 1, 1993·Canadian Journal of Psychiatry. Revue Canadienne De Psychiatrie·E PersadH Merskey
Dec 16, 1998·Journal of Child and Adolescent Psychopharmacology·D L KellyC M Ushchak
Mar 12, 1999·Biological Trace Element Research·S D DeodharP Kulhara
May 2, 2000·The British Journal of Psychiatry : the Journal of Mental Science·A M Johnston, J M Eagles

❮ Previous
Next ❯

Citations

Dec 2, 2005·Current Psychiatry Reports·Amy M Kilbourne
Nov 28, 2009·Best Practice & Research. Clinical Endocrinology & Metabolism·John H Lazarus
Apr 27, 2016·Indian Journal of Psychological Medicine·Sekh Afrar AlamHaque Nizamie
Nov 11, 2005·Journal of Psychopharmacology·Richard Morriss, Faizal Amir Mohammed
Nov 13, 2002·Pharmacoepidemiology and Drug Safety
Sep 24, 2004·Bipolar Disorders·Amy M KilbourneGretchen L Haas
Mar 8, 2019·The Australian and New Zealand Journal of Psychiatry·Fiona FairbrotherSteve Kisely
Dec 19, 2019·International Clinical Psychopharmacology·Saeed AlqahtaniYousif Asiri
Nov 22, 2019·Frontiers in Oncology·Shilpa ThakurJoanna Klubo-Gwiezdzinska
Jul 16, 2021·Neuroscience and Biobehavioral Reviews·Susana Gomes-da-CostaIsabella Pacchiarotti

❮ Previous
Next ❯

Related Concepts

Related Feeds

Bipolar Disorder

Bipolar disorder is characterized by manic and/or depressive episodes and associated with uncommon shifts in mood, activity levels, and energy. Discover the latest research this illness here.

Related Papers

The Journal of Clinical Psychiatry
H C Kales, A M Mellow
Psychiatric Services : a Journal of the American Psychiatric Association
S Pirzada Sattar, Debra A Pinals
© 2022 Meta ULC. All rights reserved