PMID: 20647640Jul 22, 2010Paper

Thyroid function and internal carotid artery stenosis in ischemic stroke

Endocrine Journal
Seul-Ki JeongHyeong-Kyu Park

Abstract

Thyroid dysfunction has been known to be closely associated with increased vascular events. The aims of the present study included determining the prevalence of subclinical thyroid disease and relationships between normal ranges of thyroid function and internal carotid artery steno-occlusion (ICS) in patients with ischemic stroke. From March 2007 to February 2008, 382 consecutive patients with ischemic stroke referred to the neurovascular ultrasound laboratory were analyzed. ICS was defined as greater than 50% luminal narrowing or complete obstruction in at least 1 internal carotid artery. Subclinical thyroid disease was determined by free thyroxine (fT4) and thyroid stimulating hormone (TSH) measurements. After the exclusion of patients with abnormal levels of thyroid hormones, normal ranges of fT4 were classified into 3 groups: low-normal (fT4, 11.0~12.3 pmol/L), mid-normal (12.4~15.4), and high-normal (15.5~24.0) thyroid groups. There were 17 patients (4.5%) with subclinical hypothyroidism and 6 (1.6%) with subclinical hyperthyroidism. There were 301 patients (78.8%) with normal fT4 and TSH levels, and among them, 67 patients (22.3%) had ICS. There was a significantly higher percentage of ICS in the low-normal thyroid group ...Continue Reading

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Citations

Jul 27, 2011·Journal of Lipids·Melpomeni PeppaGeorge Dimitriadis
Feb 13, 2015·Acta neurologica Belgica·Utkan SevukNurettin Ay
Jun 28, 2011·Journal of the Neurological Sciences·Joon-Tae KimSeul-Ki Jeong
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Sep 2, 2020·Journal of Neuro-ophthalmology : the Official Journal of the North American Neuro-Ophthalmology Society·Teruyo KidaTsunehiko Ikeda

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