Thyroid function in dietary amenorrhoea
Abnormalities of thyroid function are well known to occur in anorexia nervosa. A commoner problem is the patient with secondary amenorrhoea due to weight loss, who does not have true anorexia nervosa. Eight such patients were studied and compared to a normal control group. Total and free thyroxine, total and free triiodothyronine were found to be significantly lower in the amenorrhoea patients. No difference in basal thyroid stimulating hormone or reverse triiodothyronine levels were found. In three of four patients who had thyrotrophin releasing hormone tests performed a prolonged response was found. These results indicate that abnormal thyroid function tests may be found in this milder form of the disease. In addition, the normal reverse triiodothyronine levels suggest the possibility of two mechanisms existing, whereby T3 levels may be lowered in nutritional disorders.
Body weight and the pituitary response to hypothalamic releasing hormones in patients with anorexia nervosa
Delayed pituitary hormone response to LRF and TRF in patients with anorexia nervosa and with secondary amenorrhea associated with simple weight loss
Diversion of peripheral thyroxine metabolism from activating to inactivating pathways during complete fasting
Effects of thyrotrophin-releasing hormone on plasma levels of TSH, FSH, LH and GH in anorexia nervosa
The effect of starvation on the concentration and binding of thyroxine and triiodothyronine in serum and on the response to TRH
Estrogen replacement therapy modulates spontaneous GH secretion but does not affect GH-RH-induced GH response and low T3 syndrome in women with hypothalamic amenorrhea associated to weight-loss
Amenorrhoea, body weight and serum hormone concentrations, with particular reference to prolactin and thyroid hormones in anorexia nervosa
Anorexia nervosa (AN) is a psychiatric condition characterized by severe weight loss and secondary problems associated with malnutrition. Here is the latest research on AN.