Thyroid function in seventy-five healthy preterm infants thirty to thirty-five weeks of gestational age: a prospective and longitudinal study during the first year of life

Thyroid : Official Journal of the American Thyroid Association
Antonio CarrascosaDiego Yeste

Abstract

Thyroid function was evaluated in 75 healthy preterm infants, 30-35 weeks of gestational age. Serum thyrotropin (TSH), thyroxine (T(4)), triiodothyronine (T(3)), free T(4) (immunochemoluminescence) and reverse triiodothyronine (rT(3)) (radioimmunoassay) were measured in the mother and in the cord at delivery and in the preterm infants at 1 hour, 24 hours, 1 week, 3 weeks, 2 months, 4 months, 6 months, and 12 months of postnatal age. These values were compared to those of healthy full-term infants of the same postnatal age (22 at 24 hours from our hospital and from previously reported data at others times). Mean 24-hour TSH values were significantly lower (p < 0.001) in preterm than in full-term infant populations (12.38 +/- 6.13 microIU/mL versus 22.02 +/- 13.28 microIU/mL); however, all TSH values of preterm infants were in the range of the full-term values. Mean 24-hour free T(4) values were similar in preterm and full-term infants (1.88 +/- 0.46 ng/dL versus 2.01 +/- 0.54 ng/dL) and all preterm infants had free T(4) values within the range of those of full-term infants at 24 hours. Mean T(4) and T(3) values were significantly lower in preterm than in full-term neonates at 1 hour and 24 hours of age. Mean 24-hour rT(3) values...Continue Reading

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Citations

Mar 18, 2008·Journal of Pediatric Endocrinology & Metabolism : JPEM·Allen W Root
Dec 8, 2011·Journal of Pediatric Endocrinology & Metabolism : JPEM·Sze May NgMohammed Didi
Jul 25, 2013·Thyroid : Official Journal of the American Thyroid Association·Daisy K L ChanChin Pin Yeo
Aug 26, 2014·Early Human Development·Ki Won OhGina Lim
Dec 6, 2011·Experimental and Molecular Pathology·D Radford Shanklin
Oct 10, 2014·Journal of Perinatology : Official Journal of the California Perinatal Association·E Y ImamogluF Ovali
May 18, 2016·The Journal of Pediatrics·Luisa AguiarKsenia Tonyushkina
Jun 28, 2018·European Journal of Endocrinology·Lenore DeMartinoNorma P Tavakoli
Nov 1, 2007·The Journal of Clinical Endocrinology and Metabolism·Timothy C R PrickettBrian A Darlow
Nov 22, 2013·Journal of Pediatric Endocrinology & Metabolism : JPEM·Renee M BehmeDavid A Paul
Oct 20, 2020·International Journal of Neonatal Screening·Anna-Isabella HijmanRalph Fingerhut
Feb 7, 2021·International Journal of Neonatal Screening·Rebecca McMahonNorma P Tavakoli
Feb 10, 2021·International Journal of Neonatal Screening·Anna-Isabella HijmanRalph Fingerhut
Apr 18, 2021·Clinical Endocrinology·Nikolina Zdraveska, Mirjana Kocova
May 13, 2021·Anales de pediatría : publicación oficial de la Asociación Española de Pediatría (A.E.P.)·Susana Ares SeguraUNKNOWN en representación del Grupo de Trabajo de Tiroides de la Sociedad Española de Endocrinología Pediátrica (SEEP)
Jun 3, 2006·Pediatrics·Susan R RoseSurendra K Varma

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