Thyroid hormone and myocardial ischaemia

The Journal of Steroid Biochemistry and Molecular Biology
Constantinos PantosDennis V Cokkinos

Abstract

Thyroid hormone has various effects on the cardiovascular system and its effects on cardiac contractility, heart rhythm and vascular function has long been recognized. However, new evidence is emerged on the importance of thyroid hormone in the response of the myocardium to ischaemic stress and cardiac remodelling following myocardial infarction. Based on this new information, this review highlights the role of thyroid hormone in myocardial ischaemia and cardiac remodelling, the possible underlying mechanisms and the potential therapeutic implications. Thyroid hormone or analogs may prove new therapeutic agents for treating ischaemic heart disease.

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Citations

Dec 7, 2010·American Journal of Physiology. Heart and Circulatory Physiology·M A Hassan TalukderJay L Zweier
Nov 18, 2009·Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie·G CiniG Iervasi
Oct 30, 2016·European Journal of Pharmacology·Vanessa D OrtizAlex S R Araujo
Aug 10, 2010·Arquivos brasileiros de endocrinologia e metabologia·Laura S Ward
Mar 17, 2010·Molecular and Cellular Biochemistry·Anna IordanidouAntigone Lazou

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