Thyroid Imaging Reporting and Data System (TI-RADS): the impact of Quantitative Strain Elastography for better stratification of cancer risks

Medical Ultrasonography
Dana StoianMihaela Craciunescu

Abstract

Due to the elevated prevalence of the solid thyroid nodules in a general population, an appropriate selection of cases referred to surgery is of paramount importance. The main aim of our study was to evaluate the performance of the Thyroid Imaging Reporting and Data System (TI-RADS) as a differential diagnosis tool for thyroid nodules. We evaluated 174 nodules using TI-RADS risk stratification model, using conventional ultrasound and real time elastography parameters and linear multifrequency probe (Hitachi Preirus Machine, Hitachi Inc., Japan). All the nodules were classified using the TI-RADS system according to echogenicity, margins, shapes, calcification, lymph nodes, and increased strain ration. The results were compared with the pathology exam, which was considered the golden standard diagnosis. The prevalence of malignant nodules was 16.7% (29 cases). The differential diagnosis performance regarding the malignant tumor for TI-RADS is appropriate for clinical use, obtaining an area under ROC curve of 0.95761 [0.8424-0.989] 95% confidence interval. Combining TI-RADS 2, 3 and 4A as probably benign and TI-RADS 4B and 5 as probably malignant, the sensitivity, specificity, positive predictive value, and negative predictive val...Continue Reading

Citations

Aug 30, 2016·Ultrasound in Medicine & Biology·David CosgroveChristoph F Dietrich
Jul 19, 2016·Current Opinion in Endocrinology, Diabetes, and Obesity·Flavia MagriLuca Chiovato
Dec 11, 2019·Diagnostics·Laura CotoiDana Stoian
Apr 1, 2020·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·Raimundo Holanda Carneiro FilhoWagner Iared
Oct 31, 2020·Diagnostics·Cristina Mihaela CepehaDana Stoian

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