Abstract
The aims of this study were to stratify the risk of malignancy in thyroid incidentalomas detected on 18F-fluorodeoxyglucose positron emission tomography with computed tomography (18F-FDG PET/CT) using ultrasound features according to guidelines for thyroid nodules and to develop a subsequent management plan. From a historical cohort of 96,942 consecutive patients who underwent 18F-FDG PET/CT between October 2008 and September 2015, 1342 patients with 1364 nodules underwent ultrasound evaluation for focal uptake in thyroid gland, with a final diagnosis made for 877 patients with 907 nodules, which were included in this study. Ultrasound images were retrospectively reviewed, and they were stratified according to the American Thyroid Association and Korean Thyroid Image Reporting and Data System guidelines. The calculated malignancy risks were compared with the estimated risks suggested by the guidelines. The overall malignancy risk of thyroid incidentalomas detected on 18F-FDG PET/CT was 54.7%. When stratified according to the American Thyroid Association guidelines, the malignancy risks of thyroid incidentalomas with high and intermediate suspicion (93.2% and 45.2%, respectively) were higher than those indicated in the guideline...Continue Reading
References
Dec 14, 2001·Surgery·M S CohenJ F Moley
Sep 13, 2003·The Journal of Clinical Endocrinology and Metabolism·Keon Wook KangSun Wook Kim
Jun 4, 2005·The Laryngoscope·Tae Yong KimYoung Kee Shong
Oct 20, 2007·BMJ : British Medical Journal·Erik von ElmUNKNOWN STROBE Initiative
Apr 12, 2008·Radiology·Won-Jin MoonUNKNOWN Thyroid Study Group, Korean Society of Neuro- and Head and Neck Radiology
Jul 24, 2008·AJR. American Journal of Roentgenology·Jin Young KwakKi Keun Oh
Mar 6, 2009·Nuclear Medicine Communications·Wengen ChenAbass Alavi
Sep 22, 2009·Annals of Nuclear Medicine·Bong Joo KangSoo Kyo Chung
Oct 23, 2009·American Journal of Clinical Pathology·Edmund S CibasUNKNOWN NCI Thyroid FNA State of the Science Conference
Jan 14, 2011·Korean Journal of Radiology : Official Journal of the Korean Radiological Society·Won-Jin MoonUNKNOWN Korean Society of Radiology
Jan 20, 2011·Annals of Saudi Medicine·Ahmad AlmuhaidebJamshed Bomanji
Aug 21, 2012·The Journal of Clinical Endocrinology and Metabolism·Francesco BertagnaRaffaele Giubbini
Dec 30, 2014·European Thyroid Journal·Gilles RussLaszlo Hegedüs
Jun 18, 2015·Journal of Pathology and Translational Medicine·Chan Kwon JungUNKNOWN Korean Endocrine Pathology Thyroid Core Needle Biopsy Study Group
Oct 16, 2015·Thyroid : Official Journal of the American Thyroid Association·Bryan R HaugenLeonard Wartofsky
Dec 20, 2015·Clinical Radiology·P BeechD Nandurkar
Mar 11, 2016·Nuclear Medicine Communications·Özgür DemirMurat Faik Erdoğan
May 3, 2016·Korean Journal of Radiology : Official Journal of the Korean Radiological Society·Jung Hee ShinUNKNOWN Korean Society of Thyroid Radiology (KSThR) and Korean Society of Radiology
May 12, 2016·Endocrine Practice : Official Journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists·Hossein GharibUNKNOWN AACE/ACE/AME Task Force on Thyroid Nodules
Aug 16, 2016·Thyroid : Official Journal of the American Thyroid Association·Douglas S RossMartin A Walter
Mar 23, 2017·Journal of Otolaryngology - Head & Neck Surgery = Le Journal D'oto-rhino-laryngologie Et De Chirurgie Cervico-faciale·N HagenimanaM Belzile
Citations
Oct 24, 2019·The Journal of Clinical Endocrinology and Metabolism·Niek HugenIlse C H van Engen-van Grunsven
Jun 11, 2020·Thyroid : Official Journal of the American Thyroid Association·Luca CerianiLuca Giovanella
Aug 10, 2019·Diagnostics·Maria-Iulia LargDoina Piciu
Apr 10, 2020·Journal of Endocrinological Investigation·P TrimboliL Giovanella
Feb 28, 2019·Frontiers in Medicine·Philippe ThuillierRonan Abgral
May 2, 2020·European Radiology·Dong Hwan KimKyung Won Kim
Jun 17, 2021·Korean Journal of Radiology : Official Journal of the Korean Radiological Society·Eun Ju HaJung Hwan Baek
Nov 9, 2021·Frontiers in Endocrinology·J F de LeijerH E Westerlaan