Thyroid nodules with isolated macrocalcification: malignancy risk and diagnostic efficacy of fine-needle aspiration and core needle biopsy

Ultrasonography
Dong Gyu NaSo Lyung Jung

Abstract

This study was performed to determine the malignancy risk of thyroid nodules with isolated macrocalcification and to evaluate the diagnostic efficacy of fine-needle aspiration (FNA) and core needle biopsy (CNB). From May 2008 to December 2014, a total of 44 patients with isolated macrocalcifications were enrolled from 4,081 consecutive patients who underwent FNA or CNB at a single institution. We assessed the malignancy risk of nodules with isolated macrocalcification. We compared the diagnostic results between FNA and CNB, and the diagnostic efficacy of each procedure was evaluated by the rate of inconclusive results. We compared the diagnostic performance for malignancy between FNA and CNB with a criterion of malignant or atypia/follicular lesion of undetermined significance (indeterminate) diagnostic results. We investigated whether the ultrasonographic feature of isolated macrocalcification was predictive of malignancy. The malignancy risk of nodules with isolated macrocalcification was 16.1% in 31 nodules with final diagnoses and 11.4% in all nodules. CNB demonstrated a significantly lower rate of nondiagnostic and inconclusive results than FNA (7.7% vs. 53.8%, P=0.002 and 15.4% vs. 57.7%, P=0.003, respectively) in 26 nodu...Continue Reading

References

Apr 12, 2008·Radiology·Won-Jin MoonUNKNOWN Thyroid Study Group, Korean Society of Neuro- and Head and Neck Radiology
Sep 2, 2008·Expert Review of Anticancer Therapy·John BuscombeCaroline Witney-Smith
Nov 6, 2009·Thyroid : Official Journal of the American Thyroid Association·Edmund S Cibas, Syed Z Ali
Nov 3, 2010·World Journal of Surgery·Zhaohui LuJuming Lu
Feb 19, 2013·European Journal of Endocrinology·Gilles RussLaurence Leenhardt
Nov 28, 2013·The Journal of Clinical Endocrinology and Metabolism·Juan P BritoVictor M Montori
Feb 18, 2014·Yonsei Medical Journal·Yun Joo ParkCheong Soo Park
Mar 6, 2015·Korean Journal of Radiology : Official Journal of the Korean Radiological Society·Young Hen LeeUNKNOWN Korean Society of Radiology
Mar 10, 2015·Thyroid : Official Journal of the American Thyroid Association·Luciana Reck RemontiJorge Luiz Gross
Apr 9, 2015·Thyroid : Official Journal of the American Thyroid Association·Kyung Sik YiChul-Ho Sohn
Jun 18, 2015·Journal of Pathology and Translational Medicine·Chan Kwon JungUNKNOWN Korean Endocrine Pathology Thyroid Core Needle Biopsy Study Group

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Citations

Apr 12, 2016·Ultrasonography·Adriana Handra-Luca, Frederique Tissier
Sep 3, 2016·Korean Journal of Radiology : Official Journal of the Korean Radiological Society·Eun Ju HaJae Kyun Kim
Nov 8, 2017·Thyroid : Official Journal of the American Thyroid Association·Su Min HaSung Bin Park
Aug 10, 2017·Thyroid : Official Journal of the American Thyroid Association·Su Min HaJung Hwan Baek
Feb 21, 2019·European Radiology·Miguel PajaJosé I López
Jun 28, 2019·Scientific Reports·Shivani SharmaJames K Gimzewski
Apr 2, 2020·Thyroid : Official Journal of the American Thyroid Association·Min Ji HongHunkyung Lee
Jan 18, 2017·Korean Journal of Radiology : Official Journal of the Korean Radiological Society·Dong Gyu NaUNKNOWN Korean Society of Thyroid Radiology (KSThR) and Korean Society of Radiology
Nov 22, 2018·AJR. American Journal of Roentgenology·Dong Gyu Na, Jung Hwan Baek
Dec 31, 2020·International Journal of Molecular Sciences·Rita BonfiglioElena Bonanno
Mar 5, 2021·Korean Journal of Radiology : Official Journal of the Korean Radiological Society·Hwa Seon ShinWon Jun Kim
Jun 17, 2021·Korean Journal of Radiology : Official Journal of the Korean Radiological Society·Eun Ju HaJung Hwan Baek

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Methods Mentioned

BETA
biopsy
surgical resection

Software Mentioned

SPSS Statistics

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