Thyroid Nodules With Nondiagnostic Cytologic Results: Follow-Up Management Using Ultrasound Patterns Based on the 2015 American Thyroid Association Guidelines

AJR. American Journal of Roentgenology
Chae Jung ParkJin Young Kwak

Abstract

The purpose of this study was to evaluate the malignancy rate of nodules with nondiagnostic cytologic results based on the American Thyroid Association (ATA) ultrasound (US) patterns and to suggest management guidelines for these nodules. From January 2013 to December 2014, 441 nodules (≥ 1 cm) were found in 437 patients with nondiagnostic results of ultrasound (US)-guided fine-needle aspiration biopsy (nondiagnostic nodules). A total of 191 nodules that were cytopathologically confirmed or were smaller (> 3 mm) at follow-up US were enrolled. The US findings of each nodule were reviewed. One radiologist classified the nodules into the following five categories according to the 2015 ATA guidelines: high, intermediate, low, and very low suspicion for malignancy and benign. The reference standard was histopathologic confirmation. Nodules that were smaller at follow-up US were considered benign. The malignancy rate of each category was calculated. Among a total 191 nodules, 20 (10.5%) were malignant. Solid composition, marked hypoechogenicity, microlobulated or irregular margins, microcalcifications, and taller-than-wide shape were more frequently seen in malignant nodules (all p < 0.001). The malignancy rate of nodules with very l...Continue Reading

References

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Citations

Jun 4, 2020·The Journal of Clinical Endocrinology and Metabolism·Giorgio GraniCosimo Durante
Jun 25, 2020·Endocrine Practice : Official Journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists·Florentino Carral San LaureanoMaría Del Carmen Ayala Ortega
Jan 21, 2021·Endocrine Practice : Official Journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists·Florentino Carral San LaureanoMaría Del Carmen Ayala Ortega

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