PMID: 6406110Jan 1, 1983Paper

Thyroid status in various degrees of protein-calorie malnutrition in children

Clinical Endocrinology
C OnuoraK M Etta

Abstract

The thyroid functional parameters of 102 children with protein-calorie malnutrition (PCM) classified as undernourished, marasmic, kwashiorkor and marasmic-kwashiorkor were studied by measuring the serum T4, T3, T3 percentage uptake (T3%UT), free thyroxine index (FTI), and (in a few subjects) TSH. Total plasma proteins, albumin and globulin were also estimated. T4 was increased markedly in the undernourished children and significantly decreased in kwashiorkor and marasmic-kwashiorkor groups. There was a consistent and significant fall in T3 levels of all PCM children. From normal values, the fall in T3 levels was progressive in the order of undernourished, marasmic, kwashiorkor and the marasmic-kwashiorkor states. The T3%UT was increased above normal in the marasmic, kwashiorkor and marasmic-kwashiorkor conditions. The FTI decreased somewhat in marasmus and kwashiorkor groups and was very low in marasmic-kwashiorkor. Total protein and albumin levels were above normal in the undernourished but became markedly depressed in the marasmic-kwashiorkor children. The changes in the levels of both T4 and T3 in our observations are well correlated with the levels of plasma proteins in the undernourished, marasmic and kwashiorkor states bu...Continue Reading

References

Jul 1, 1979·The Journal of Nutrition·O L TulpE S Horton
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Citations

Dec 3, 2009·Nutrition & Metabolism·Kazeem A Oshikoya, Idowu O Senbanjo
Dec 7, 2018·Current Opinion in Endocrinology, Diabetes, and Obesity·Jasreena K Nijjar, Diane Stafford
Aug 11, 2000·Pathology Oncology Research : POR·M SalehniaT Al-Traihi
Jan 1, 1987·Virchows Archiv. B, Cell Pathology Including Molecular Pathology·J CatalaE Hollande
Sep 1, 1986·The British Journal of Nutrition·M B Duggan, R D Milner
May 1, 2002·Plant Disease·Jason A SmithN A Anderson
Mar 25, 2000·The American Journal of Clinical Nutrition·C D Capo-ChichiM Vidailhet

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