PMID: 8948423Jun 15, 1995Paper

Thyroidal extracellular glutathione peroxidase: a potential regulator of thyroid-hormone synthesis

The Biochemical Journal
A F HowieG J Beckett

Abstract

Human thyrocytes were found to synthesize and secrete the selenoenzyme extracellular glutathione peroxidase (E-GPX), a process which was controlled by the Ca2+/phosphoinositol second-messenger cascade. The potential involvement of thyroidal E-GPX in the regulation of thyroid-hormone synthesis and in the protection of the thyrocyte from peroxidative damage is discussed.

Citations

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