Thyrotoxic hypokalemic periodic paralysis: six cases in non-Asian patients.

Endocrine Practice : Official Journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists
D L GordonA M Lawrence

Abstract

To describe six cases of thyrotoxic hypokalemic periodic paralysis (THPP) in non-Asian men. We present six cases of THPP, including clinical and laboratory findings, treatment, and outcome, and review the related literature. Hypokalemic periodic paralysis is a relatively common occurrence in Asian men with thyrotoxicosis; however, it is unusual in non-Asian patients with thyrotoxicosis. Among our six patients--four Caucasians, one African-American, and one Hispanic--the precipitating factors, initial manifestations, and clinical course varied. In general, treatment with 131 I or potassium eliminated the paralytic episodes. THPP needs to be distinguished from nonthyrotoxic hypokalemic periodic paralysis. Although THPP is unusual in non-Asian men, it must be recognized because of the severe and potentially fatal complications, which are reversible with potassium replacement and antithyroid therapy.

References

Sep 1, 1978·Proceedings of the National Academy of Sciences of the United States of America·R A DavisF R Simon
Sep 30, 1978·British Medical Journal·P P YeoJ S Cheah
Nov 2, 1991·BMJ : British Medical Journal·A ChanR Swaminathan
Jul 9, 1987·Neuroscience Letters·M GuerraM Mas
May 1, 1987·The Journal of Clinical Endocrinology and Metabolism·H TamaiS Nagataki
Apr 1, 1972·Metabolism: Clinical and Experimental·Y ShishibaK Shizume
Mar 22, 1969·British Medical Journal·A J McFadzean, R Yeung
Feb 25, 1967·British Medical Journal·A J McFadzean, R Yeung
Dec 8, 1983·The New England Journal of Medicine·M J BrownM B Murphy
Jan 1, 1994·Thyroid : Official Journal of the American Thyroid Association·R E KilpatrickS N Levine
Aug 1, 1994·Clinical Endocrinology·A ChanR Swaminathan
Nov 1, 1994·Human Genetics·E PlassartJ Weissenbach
Oct 1, 1994·Annals of Emergency Medicine·P Shayne, A Hart
Mar 1, 1994·Journal of the Neurological Sciences·T P LinksH J Oosterhuis
Jun 1, 1996·QJM : Monthly Journal of the Association of Physicians·G T KoC S Cockram
Dec 1, 1957·The Journal of Clinical Endocrinology and Metabolism·S OKINAKAT ITO
Feb 1, 1961·The American Journal of Medicine·A G ENGEL
Sep 1, 1963·Neurology·E SATOYOSHIY NISHIYAMA

❮ Previous
Next ❯

Citations

Jul 2, 2015·The New England Journal of Medicine·Michelle L GumzCharles S Wingo
May 11, 2011·Nature Reviews. Endocrinology·Rui M B MacielMagnus R Dias da Silva
Feb 2, 2006·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Geoffrey W AbbottSteve A N Goldstein
Mar 8, 2008·Annals of Clinical Biochemistry·Francesco VendrameSusanna Morano

❮ Previous
Next ❯

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Endocrine Practice : Official Journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists
Prakensh SeshadriNaygar Iqbal
La Revue de médecine interne
C Chatot-HenryG Sobesky
© 2022 Meta ULC. All rights reserved