PMID: 3751452Jul 1, 1986Paper

Thyrotropin--an episodically secreted hormone

Acta Endocrinologica
G BrabantA von zur Mühlen

Abstract

A recently developed highly sensitive immunoradiometric thyrotropin (TSH) assay capable to distinguish between euthyroid and hyperthyroid TSH-levels was used to evaluate the secretion-pattern of TSH in 10 healthy male subjects by taking blood via an indwelling venous catheter at 10 min intervals over 24 h. Visual analysis revealed a pulsatile pattern of hormone release with an average of 10.3 peaks/24 h. Evaluation by computer assisted programs such as the Santen-program (8.9 peaks/24 h, amplitude 0.60 mU TSH/l), the 'Pulsar'-program (6 peaks/24 h, amplitude 0.61 mU TSH/l) or power-spectrum analysis (11.9 peaks/24 h) showed similar results. These data suggest a pulsatile mechanism of TSH secretion similar to other pituitary hormones.

Citations

May 15, 1989·Klinische Wochenschrift·I VardarliK H Usadel
Feb 1, 1989·Biochimie·G BrabantR D Hesch
Jan 1, 1995·Psychoneuroendocrinology·R FiascheM Holland
Mar 4, 2000·Domestic Animal Endocrinology·H S KooistraA Rijnberk
Feb 1, 2013·Journal of Thyroid Research·Johannes W DietrichElisavet H Fotiadou
Jan 1, 1988·Chronobiology International·J SalvadorM F Scanlon
Apr 1, 1993·Kidney International·A J Felsenfeld, F Llach
May 1, 1993·IEEE Transactions on Bio-medical Engineering·G De Nicolao, D Liberati
Jul 1, 1992·Trends in Endocrinology and Metabolism : TEM·G BrabantC Schofl
Jul 1, 1988·Clinical Endocrinology·P C HindmarshC G Brook
Dec 4, 2003·Thyroid : Official Journal of the American Thyroid Association·Stig AndersenPeter Laurberg
Dec 1, 1991·Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology·W G Rossmanith, C Lauritzen
Dec 1, 1988·The American Journal of Physiology·V GuardabassoD Rodbard

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