Tiara[ n]uril: A Glycoluril-Based Macrocyclic Host with Cationic Walls

The Journal of Organic Chemistry
Pradeep Kumar ChandrakumarAnthony I Day

Abstract

The synthesis of new cationic macrocyclic host molecules is described. These macrocycles are comprised of glycoluril oligomers linked to two pyrazolium groups, which form part of a cationic wall facing into their cavities. A number of derivatives have been prepared with an objective to increasing the cavity size, and each new product has been fully characterized. Preliminary investigations of p Kas of Me10Tu[3]2+ and an interaction of L-glutamine indicate a potential for binding anionic molecules that also carry H-bond donor groups.

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Citations

Feb 20, 2020·Chemical Communications : Chem Comm·Rajni DhimanAnthony I Day

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