PMID: 11340586May 8, 2001Paper

Time- and depth-dependent changes in crosslinking and oxidation of shelf-aged polyethylene acetabular liners

Journal of Biomedical Materials Research
R J JacobJ Higgins

Abstract

Since crosslinking and oxidation of ultrahigh-molecular-weight polyethylene (UHMWPE) have important roles in determining the wear resistance of UHMWPE total joint components, the time and depth dependence of crosslinking and oxidation of new shelf-aged (2-11 years), ready-to-implant acetabular liners were studied by using solvent extraction and Fourier transform infrared spectroscopy. The ultrastructure of these materials also was examined by using low-voltage scanning electron microscopy in an oil-free vacuum. Oxidation levels increased with time and with depth (p < 0.0001) from the surface of the older liners to a maximum value at about 1-2 mm below the surface, then decreased. They were minimal at the midsection of the liners. The crosslinking of these liners decreased with time and depth (p < 0.0001) and was inversely proportional to the level of oxidation. High and depth-dependent oxidation levels were observed in all older liners made from GUR 415 and 412 resins but were distinctly absent from a comparably aged (i.e., 9 years) liner made from 1900 CM-resin. Some liners showed varying degrees of inhomogeneous and discontinuous morphologic ultrastructure in addition to varying amounts of porosity while others had a more hom...Continue Reading

References

Jul 1, 1979·Journal of Biomedical Materials Research·H J Nusbaum, R M Rose
Nov 1, 1984·Journal of Biomedical Materials Research·P Eyerer, Y C Ke
Jul 1, 1994·The Journal of Bone and Joint Surgery. American Volume·C M RimnacT M Wright
Dec 1, 1993·Biomedizinische Technik. Biomedical Engineering·R M Streicher
Jun 1, 1993·The Journal of Bone and Joint Surgery. American Volume·S R GoldringT M Wright
Oct 1, 1995·Journal of Biomedical Materials Research·D PienkowskiP J Nicholls
Jan 1, 1996·Journal of Biomedical Materials Research·D PienkowskiH Kaufer
Oct 1, 1996·Clinical Orthopaedics and Related Research·S E WhiteL A Whiteside
Jan 1, 1997·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·S M KurtzD L Bartel
Nov 25, 1998·Journal of Biomedical Materials Research·B M Daly, J Yin
Apr 30, 1999·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·H McKellopR Salovey

❮ Previous
Next ❯

Citations

Aug 13, 2008·Journal of Orthopaedic Science : Official Journal of the Japanese Orthopaedic Association·Katsutoshi HaraTakehiko Torisu
Nov 12, 2010·Journal of Biomaterials Science. Polymer Edition·Giuseppe PezzottiNobuhiko Sugano
Jun 7, 2008·The Journal of Arthroplasty·Mark A KlaassenDelfino Carranza Guzman
Dec 4, 2013·Proceedings of the Institution of Mechanical Engineers. Part H, Journal of Engineering in Medicine·Abdellatif AbdelgaiedJohn Fisher
Mar 23, 2013·Proceedings of the Institution of Mechanical Engineers. Part H, Journal of Engineering in Medicine·Abdellatif AbdelgaiedZhongmin Jin

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Journal of Biomedical Materials Research. Part B, Applied Biomaterials
Steven M KurtzJ Dumbleton
The Journal of Arthroplasty
John J CallaghanRichard C Johnston
Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society
Steven M KurtzD L Bartel
© 2021 Meta ULC. All rights reserved