PMID: 5919562Apr 1, 1966

Time course and nature of temperature-induced changes in sodium-glucose interactions of the goldfish intestine

The Journal of Physiology
M W Smith


1. Glucose-evoked potentials measured at low incubation temperatures were found to be highly temperature dependent (phase 1), but less so at high incubation temperatures (phase 2) and acclimatization of an 8 degrees C fish to 25 degrees C resulted in the extension of phase 1 up to the environmental temperature of the fish. This change was only part of the mechanism controlling the acclimatization of sodium transport across the intestine.2. The temperature at which the glucose-evoked potential changed from phase 1 to phase 2 was approximately equal to the temperature at which glucose began to raise the steady transmural potential of the intestine.3. No changes in intestinal electrical parameters could be detected when fish, acclimatized to 8 degrees C, were heated at 25 degrees C for 15 hr, but after 20 hr at the higher temperature, acclimatization to the new temperature was complete.4. Intestines from fish acclimatized to 8 degrees C, but which had first spent 15 hr at 25 degrees C and then 10 hr at 8 degrees C, still behaved qualitatively like 8 degrees C - intestines but the magnitude of the glucose-evoked potentials was slightly reduced.5. It is suggested as a working hypothesis that acclimatization of the sodium-glucose int...Continue Reading


Sep 4, 2014·Journal of Comparative Physiology. B, Biochemical, Systemic, and Environmental Physiology·Sunita R NadellaChris M Wood

Related Concepts

Glucose, (beta-D)-Isomer

Trending Feeds


Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Alzheimer's Disease: MS4A

Variants within the membrane-spanning 4-domains subfamily A (MS4A) gene cluster have recently been implicated in Alzheimer's disease in genome-wide association studies. Here is the latest research on Alzheimer's disease and MS4A.

Pediculosis pubis

Pediculosis pubis is a disease caused by a parasitic insect known as Pthirus pubis, which infests human pubic hair, as well as other areas with hair including eye lashes. Here is the latest research.

Rh Isoimmunization

Rh isoimmunization is a potentially preventable condition that occasionally is associated with significant perinatal morbidity or mortality. Discover the latest research on Rh Isoimmunization here.

Genetic Screens in iPSC-derived Brain Cells

Genetic screening is a critical tool that can be employed to define and understand gene function and interaction. This feed focuses on genetic screens conducted using induced pluripotent stem cell (iPSC)-derived brain cells. It also follows CRISPR-Cas9 approaches to generating genetic mutants as a means of understanding the effect of genetics on phenotype.

Enzyme Evolution

This feed focuses on molecular models of enzyme evolution and new approaches (such as adaptive laboratory evolution) to metabolic engineering of microorganisms. Here is the latest research.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Pharmacology of Proteinopathies

This feed focuses on the pharmacology of proteinopathies - diseases in which proteins abnormally aggregate (i.e. Alzheimer’s, Parkinson’s, etc.). Discover the latest research in this field with this feed.

Alignment-free Sequence Analysis Tools

Alignment-free sequence analyses have been applied to problems ranging from whole-genome phylogeny to the classification of protein families, identification of horizontally transferred genes, and detection of recombined sequences. Here is the latest research.